Exploring TCGA

Load dependencies

library(tidyverse)

── Attaching packages ───────────────────────────────────────────────────────── tidyverse 1.2.1 ──
✔ ggplot2 2.2.1     ✔ purrr   0.2.4
✔ tibble  1.4.2     ✔ dplyr   0.7.4
✔ tidyr   0.8.0     ✔ stringr 1.3.0
✔ readr   1.1.1     ✔ forcats 0.3.0
── Conflicts ──────────────────────────────────────────────────────────── tidyverse_conflicts() ──
✖ dplyr::filter() masks stats::filter()
✖ dplyr::lag()    masks stats::lag()

library(cowplot)

Attaching package: ‘cowplot’

The following object is masked from ‘package:ggplot2’:

    ggsave

1 Reading & Cleaning

Define where the data lives

## Define data paths
in_path_varscan = 'data/maf/6c93f518-1956-4435-9806-37185266d248/TCGA.BRCA.varscan.6c93f518-1956-4435-9806-37185266d248.DR-10.0.somatic.maf.gz'
in_path_muse = 'data/maf/b8ca5856-9819-459c-87c5-94e91aca4032/TCGA.BRCA.muse.b8ca5856-9819-459c-87c5-94e91aca4032.DR-10.0.somatic.maf.gz'
in_path_ss = 'data/maf/7dd592e3-5950-4438-96d5-3c718aca3f13/TCGA.BRCA.somaticsniper.7dd592e3-5950-4438-96d5-3c718aca3f13.DR-10.0.somatic.maf.gz'
in_path_mutect = 'data/maf/995c0111-d90b-4140-bee7-3845436c3b42/TCGA.BRCA.mutect.995c0111-d90b-4140-bee7-3845436c3b42.DR-10.0.somatic.maf.gz'

Reading data

df = read_tsv(
  in_path_mutect,
  comment = '#'
)

Parsed with column specification:
cols(
  .default = col_character(),
  Entrez_Gene_Id = col_integer(),
  Start_Position = col_integer(),
  End_Position = col_integer(),
  t_depth = col_integer(),
  t_ref_count = col_integer(),
  t_alt_count = col_integer(),
  n_depth = col_integer(),
  ALLELE_NUM = col_integer(),
  DISTANCE = col_integer(),
  TRANSCRIPT_STRAND = col_integer(),
  GMAF = col_double(),
  AFR_MAF = col_double(),
  AMR_MAF = col_double(),
  EAS_MAF = col_double(),
  EUR_MAF = col_double(),
  SAS_MAF = col_double(),
  AA_MAF = col_double(),
  EA_MAF = col_double(),
  PUBMED = col_integer(),
  PICK = col_integer()
  # ... with 13 more columns
)
See spec(...) for full column specifications.

|======                                                                                                                                                                                           |   3%    5 MB
|======                                                                                                                                                                                           |   3%    5 MB
|======                                                                                                                                                                                           |   3%    5 MB
|======                                                                                                                                                                                           |   3%    5 MB
|======                                                                                                                                                                                           |   3%    6 MB
|=======                                                                                                                                                                                          |   3%    6 MB
|=======                                                                                                                                                                                          |   3%    6 MB
|=======                                                                                                                                                                                          |   3%    6 MB
|=======                                                                                                                                                                                          |   3%    6 MB
|=======                                                                                                                                                                                          |   3%    6 MB
|=======                                                                                                                                                                                          |   4%    6 MB
|=======                                                                                                                                                                                          |   4%    6 MB
|========                                                                                                                                                                                         |   4%    6 MB
|========                                                                                                                                                                                         |   4%    7 MB
|========                                                                                                                                                                                         |   4%    7 MB
|========                                                                                                                                                                                         |   4%    7 MB
|========                                                                                                                                                                                         |   4%    7 MB
|========                                                                                                                                                                                         |   4%    7 MB
|========                                                                                                                                                                                         |   4%    7 MB
|=========                                                                                                                                                                                        |   4%    7 MB
|=========                                                                                                                                                                                        |   4%    7 MB
|=========                                                                                                                                                                                        |   4%    8 MB
|=========                                                                                                                                                                                        |   4%    8 MB
|=========                                                                                                                                                                                        |   4%    8 MB
|=========                                                                                                                                                                                        |   5%    8 MB
|=========                                                                                                                                                                                        |   5%    8 MB
|=========                                                                                                                                                                                        |   5%    8 MB
|==========                                                                                                                                                                                       |   5%    8 MB
|==========                                                                                                                                                                                       |   5%    8 MB
|==========                                                                                                                                                                                       |   5%    8 MB
|==========                                                                                                                                                                                       |   5%    9 MB
|==========                                                                                                                                                                                       |   5%    9 MB
|==========                                                                                                                                                                                       |   5%    9 MB
|==========                                                                                                                                                                                       |   5%    9 MB
|===========                                                                                                                                                                                      |   5%    9 MB
|===========                                                                                                                                                                                      |   5%    9 MB
|===========                                                                                                                                                                                      |   5%    9 MB
|===========                                                                                                                                                                                      |   5%    9 MB
|===========                                                                                                                                                                                      |   5%   10 MB
|===========                                                                                                                                                                                      |   6%   10 MB
|===========                                                                                                                                                                                      |   6%   10 MB
|===========                                                                                                                                                                                      |   6%   10 MB
|============                                                                                                                                                                                     |   6%   10 MB
|============                                                                                                                                                                                     |   6%   10 MB
|============                                                                                                                                                                                     |   6%   10 MB
|============                                                                                                                                                                                     |   6%   10 MB
|============                                                                                                                                                                                     |   6%   10 MB
|============                                                                                                                                                                                     |   6%   11 MB
|============                                                                                                                                                                                     |   6%   11 MB
|=============                                                                                                                                                                                    |   6%   11 MB
|=============                                                                                                                                                                                    |   6%   11 MB
|=============                                                                                                                                                                                    |   6%   11 MB
|=============                                                                                                                                                                                    |   6%   11 MB
|=============                                                                                                                                                                                    |   7%   11 MB
|=============                                                                                                                                                                                    |   7%   11 MB
|=============                                                                                                                                                                                    |   7%   11 MB
|=============                                                                                                                                                                                    |   7%   12 MB
|==============                                                                                                                                                                                   |   7%   12 MB
|==============                                                                                                                                                                                   |   7%   12 MB
|==============                                                                                                                                                                                   |   7%   12 MB
|==============                                                                                                                                                                                   |   7%   12 MB
|==============                                                                                                                                                                                   |   7%   12 MB
|==============                                                                                                                                                                                   |   7%   12 MB
|==============                                                                                                                                                                                   |   7%   12 MB
|===============                                                                                                                                                                                  |   7%   12 MB
|===============                                                                                                                                                                                  |   7%   13 MB
|===============                                                                                                                                                                                  |   7%   13 MB
|===============                                                                                                                                                                                  |   7%   13 MB
|===============                                                                                                                                                                                  |   8%   13 MB
|===============                                                                                                                                                                                  |   8%   13 MB
|===============                                                                                                                                                                                  |   8%   13 MB
|===============                                                                                                                                                                                  |   8%   13 MB
|================                                                                                                                                                                                 |   8%   13 MB
|================                                                                                                                                                                                 |   8%   13 MB
|================                                                                                                                                                                                 |   8%   14 MB
|================                                                                                                                                                                                 |   8%   14 MB
|================                                                                                                                                                                                 |   8%   14 MB
|================                                                                                                                                                                                 |   8%   14 MB
|================                                                                                                                                                                                 |   8%   14 MB
|=================                                                                                                                                                                                |   8%   14 MB
|=================                                                                                                                                                                                |   8%   14 MB
|=================                                                                                                                                                                                |   8%   14 MB
|=================                                                                                                                                                                                |   8%   15 MB
|=================                                                                                                                                                                                |   9%   15 MB
|=================                                                                                                                                                                                |   9%   15 MB
|=================                                                                                                                                                                                |   9%   15 MB
|=================                                                                                                                                                                                |   9%   15 MB
|==================                                                                                                                                                                               |   9%   15 MB
|==================                                                                                                                                                                               |   9%   15 MB
|==================                                                                                                                                                                               |   9%   15 MB
|==================                                                                                                                                                                               |   9%   15 MB
|==================                                                                                                                                                                               |   9%   16 MB
|==================                                                                                                                                                                               |   9%   16 MB
|==================                                                                                                                                                                               |   9%   16 MB
|===================                                                                                                                                                                              |   9%   16 MB
|===================                                                                                                                                                                              |   9%   16 MB
|===================                                                                                                                                                                              |   9%   16 MB
|===================                                                                                                                                                                              |  10%   16 MB
|===================                                                                                                                                                                              |  10%   16 MB
|===================                                                                                                                                                                              |  10%   16 MB
|===================                                                                                                                                                                              |  10%   17 MB
|===================                                                                                                                                                                              |  10%   17 MB
|====================                                                                                                                                                                             |  10%   17 MB
|====================                                                                                                                                                                             |  10%   17 MB
|====================                                                                                                                                                                             |  10%   17 MB
|====================                                                                                                                                                                             |  10%   17 MB
|====================                                                                                                                                                                             |  10%   17 MB
|====================                                                                                                                                                                             |  10%   17 MB
|====================                                                                                                                                                                             |  10%   18 MB
|=====================                                                                                                                                                                            |  10%   18 MB
|=====================                                                                                                                                                                            |  10%   18 MB
|=====================                                                                                                                                                                            |  10%   18 MB
|=====================                                                                                                                                                                            |  11%   18 MB
|=====================                                                                                                                                                                            |  11%   18 MB
|=====================                                                                                                                                                                            |  11%   18 MB
|=====================                                                                                                                                                                            |  11%   18 MB
|======================                                                                                                                                                                           |  11%   18 MB
|======================                                                                                                                                                                           |  11%   19 MB
|======================                                                                                                                                                                           |  11%   19 MB
|======================                                                                                                                                                                           |  11%   19 MB
|======================                                                                                                                                                                           |  11%   19 MB
|======================                                                                                                                                                                           |  11%   19 MB
|======================                                                                                                                                                                           |  11%   19 MB
|======================                                                                                                                                                                           |  11%   19 MB
|=======================                                                                                                                                                                          |  11%   19 MB
|=======================                                                                                                                                                                          |  11%   20 MB
|=======================                                                                                                                                                                          |  12%   20 MB
|=======================                                                                                                                                                                          |  12%   20 MB
|=======================                                                                                                                                                                          |  12%   20 MB
|=======================                                                                                                                                                                          |  12%   20 MB
|=======================                                                                                                                                                                          |  12%   20 MB
|========================                                                                                                                                                                         |  12%   20 MB
|========================                                                                                                                                                                         |  12%   20 MB
|========================                                                                                                                                                                         |  12%   20 MB
|========================                                                                                                                                                                         |  12%   21 MB
|========================                                                                                                                                                                         |  12%   21 MB
|========================                                                                                                                                                                         |  12%   21 MB
|========================                                                                                                                                                                         |  12%   21 MB
|=========================                                                                                                                                                                        |  12%   21 MB
|=========================                                                                                                                                                                        |  12%   21 MB
|=========================                                                                                                                                                                        |  13%   21 MB
|=========================                                                                                                                                                                        |  13%   21 MB
|=========================                                                                                                                                                                        |  13%   22 MB
|=========================                                                                                                                                                                        |  13%   22 MB
|=========================                                                                                                                                                                        |  13%   22 MB
|=========================                                                                                                                                                                        |  13%   22 MB
|==========================                                                                                                                                                                       |  13%   22 MB
|==========================                                                                                                                                                                       |  13%   22 MB
|==========================                                                                                                                                                                       |  13%   22 MB
|==========================                                                                                                                                                                       |  13%   22 MB
|==========================                                                                                                                                                                       |  13%   23 MB
|==========================                                                                                                                                                                       |  13%   23 MB
|==========================                                                                                                                                                                       |  13%   23 MB
|===========================                                                                                                                                                                      |  13%   23 MB
|===========================                                                                                                                                                                      |  14%   23 MB
|===========================                                                                                                                                                                      |  14%   23 MB
|===========================                                                                                                                                                                      |  14%   23 MB
|===========================                                                                                                                                                                      |  14%   23 MB
|===========================                                                                                                                                                                      |  14%   23 MB
|===========================                                                                                                                                                                      |  14%   24 MB
|===========================                                                                                                                                                                      |  14%   24 MB
|============================                                                                                                                                                                     |  14%   24 MB
|============================                                                                                                                                                                     |  14%   24 MB
|============================                                                                                                                                                                     |  14%   24 MB
|============================                                                                                                                                                                     |  14%   24 MB
|============================                                                                                                                                                                     |  14%   24 MB
|============================                                                                                                                                                                     |  14%   24 MB
|============================                                                                                                                                                                     |  14%   24 MB
|=============================                                                                                                                                                                    |  14%   25 MB
|=============================                                                                                                                                                                    |  15%   25 MB
|=============================                                                                                                                                                                    |  15%   25 MB
|=============================                                                                                                                                                                    |  15%   25 MB
|=============================                                                                                                                                                                    |  15%   25 MB
|=============================                                                                                                                                                                    |  15%   25 MB
|=============================                                                                                                                                                                    |  15%   25 MB
|=============================                                                                                                                                                                    |  15%   25 MB
|==============================                                                                                                                                                                   |  15%   25 MB
|==============================                                                                                                                                                                   |  15%   26 MB
|==============================                                                                                                                                                                   |  15%   26 MB
|==============================                                                                                                                                                                   |  15%   26 MB
|==============================                                                                                                                                                                   |  15%   26 MB
|==============================                                                                                                                                                                   |  15%   26 MB
|==============================                                                                                                                                                                   |  15%   26 MB
|===============================                                                                                                                                                                  |  16%   26 MB
|===============================                                                                                                                                                                  |  16%   26 MB
|===============================                                                                                                                                                                  |  16%   27 MB
|===============================                                                                                                                                                                  |  16%   27 MB
|===============================                                                                                                                                                                  |  16%   27 MB
|===============================                                                                                                                                                                  |  16%   27 MB
|===============================                                                                                                                                                                  |  16%   27 MB
|===============================                                                                                                                                                                  |  16%   27 MB
|================================                                                                                                                                                                 |  16%   27 MB
|================================                                                                                                                                                                 |  16%   27 MB
|================================                                                                                                                                                                 |  16%   27 MB
|================================                                                                                                                                                                 |  16%   28 MB
|================================                                                                                                                                                                 |  16%   28 MB
|================================                                                                                                                                                                 |  16%   28 MB
|================================                                                                                                                                                                 |  16%   28 MB
|=================================                                                                                                                                                                |  17%   28 MB
|=================================                                                                                                                                                                |  17%   28 MB
|=================================                                                                                                                                                                |  17%   28 MB
|=================================                                                                                                                                                                |  17%   28 MB
|=================================                                                                                                                                                                |  17%   29 MB
|=================================                                                                                                                                                                |  17%   29 MB
|=================================                                                                                                                                                                |  17%   29 MB
|==================================                                                                                                                                                               |  17%   29 MB
|==================================                                                                                                                                                               |  17%   29 MB
|==================================                                                                                                                                                               |  17%   29 MB
|==================================                                                                                                                                                               |  17%   29 MB
|==================================                                                                                                                                                               |  17%   29 MB
|==================================                                                                                                                                                               |  17%   29 MB
|==================================                                                                                                                                                               |  17%   30 MB
|==================================                                                                                                                                                               |  18%   30 MB
|===================================                                                                                                                                                              |  18%   30 MB
|===================================                                                                                                                                                              |  18%   30 MB
|===================================                                                                                                                                                              |  18%   30 MB
|===================================                                                                                                                                                              |  18%   30 MB
|===================================                                                                                                                                                              |  18%   30 MB
|===================================                                                                                                                                                              |  18%   30 MB
|===================================                                                                                                                                                              |  18%   31 MB
|====================================                                                                                                                                                             |  18%   31 MB
|====================================                                                                                                                                                             |  18%   31 MB
|====================================                                                                                                                                                             |  18%   31 MB
|====================================                                                                                                                                                             |  18%   31 MB
|====================================                                                                                                                                                             |  18%   31 MB
|====================================                                                                                                                                                             |  18%   31 MB
|====================================                                                                                                                                                             |  19%   31 MB
|=====================================                                                                                                                                                            |  19%   31 MB
|=====================================                                                                                                                                                            |  19%   32 MB
|=====================================                                                                                                                                                            |  19%   32 MB
|=====================================                                                                                                                                                            |  19%   32 MB
|=====================================                                                                                                                                                            |  19%   32 MB
|=====================================                                                                                                                                                            |  19%   32 MB
|=====================================                                                                                                                                                            |  19%   32 MB
|=====================================                                                                                                                                                            |  19%   32 MB
|======================================                                                                                                                                                           |  19%   32 MB
|======================================                                                                                                                                                           |  19%   32 MB
|======================================                                                                                                                                                           |  19%   33 MB
|======================================                                                                                                                                                           |  19%   33 MB
|======================================                                                                                                                                                           |  19%   33 MB
|======================================                                                                                                                                                           |  19%   33 MB
|======================================                                                                                                                                                           |  20%   33 MB
|=======================================                                                                                                                                                          |  20%   33 MB
|=======================================                                                                                                                                                          |  20%   33 MB
|=======================================                                                                                                                                                          |  20%   33 MB
|=======================================                                                                                                                                                          |  20%   34 MB
|=======================================                                                                                                                                                          |  20%   34 MB
|=======================================                                                                                                                                                          |  20%   34 MB
|=======================================                                                                                                                                                          |  20%   34 MB
|=======================================                                                                                                                                                          |  20%   34 MB
|========================================                                                                                                                                                         |  20%   34 MB
|========================================                                                                                                                                                         |  20%   34 MB
|========================================                                                                                                                                                         |  20%   34 MB
|========================================                                                                                                                                                         |  20%   34 MB
|========================================                                                                                                                                                         |  20%   35 MB
|========================================                                                                                                                                                         |  20%   35 MB
|========================================                                                                                                                                                         |  21%   35 MB
|=========================================                                                                                                                                                        |  21%   35 MB
|=========================================                                                                                                                                                        |  21%   35 MB
|=========================================                                                                                                                                                        |  21%   35 MB
|=========================================                                                                                                                                                        |  21%   35 MB
|=========================================                                                                                                                                                        |  21%   35 MB
|=========================================                                                                                                                                                        |  21%   35 MB
|=========================================                                                                                                                                                        |  21%   36 MB
|=========================================                                                                                                                                                        |  21%   36 MB
|==========================================                                                                                                                                                       |  21%   36 MB
|==========================================                                                                                                                                                       |  21%   36 MB
|==========================================                                                                                                                                                       |  21%   36 MB
|==========================================                                                                                                                                                       |  21%   36 MB
|==========================================                                                                                                                                                       |  21%   36 MB
|==========================================                                                                                                                                                       |  22%   36 MB
|==========================================                                                                                                                                                       |  22%   37 MB
|==========================================                                                                                                                                                       |  22%   37 MB
|===========================================                                                                                                                                                      |  22%   37 MB
|===========================================                                                                                                                                                      |  22%   37 MB
|===========================================                                                                                                                                                      |  22%   37 MB
|===========================================                                                                                                                                                      |  22%   37 MB
|===========================================                                                                                                                                                      |  22%   37 MB
|===========================================                                                                                                                                                      |  22%   37 MB
|===========================================                                                                                                                                                      |  22%   37 MB
|============================================                                                                                                                                                     |  22%   38 MB
|============================================                                                                                                                                                     |  22%   38 MB
|============================================                                                                                                                                                     |  22%   38 MB
|============================================                                                                                                                                                     |  22%   38 MB
|============================================                                                                                                                                                     |  22%   38 MB
|============================================                                                                                                                                                     |  23%   38 MB
|============================================                                                                                                                                                     |  23%   38 MB
|============================================                                                                                                                                                     |  23%   38 MB
|=============================================                                                                                                                                                    |  23%   38 MB
|=============================================                                                                                                                                                    |  23%   39 MB
|=============================================                                                                                                                                                    |  23%   39 MB
|=============================================                                                                                                                                                    |  23%   39 MB
|=============================================                                                                                                                                                    |  23%   39 MB
|=============================================                                                                                                                                                    |  23%   39 MB
|=============================================                                                                                                                                                    |  23%   39 MB
|==============================================                                                                                                                                                   |  23%   39 MB
|==============================================                                                                                                                                                   |  23%   39 MB
|==============================================                                                                                                                                                   |  23%   40 MB
|==============================================                                                                                                                                                   |  23%   40 MB
|==============================================                                                                                                                                                   |  24%   40 MB
|==============================================                                                                                                                                                   |  24%   40 MB
|==============================================                                                                                                                                                   |  24%   40 MB
|===============================================                                                                                                                                                  |  24%   40 MB
|===============================================                                                                                                                                                  |  24%   40 MB
|===============================================                                                                                                                                                  |  24%   40 MB
|===============================================                                                                                                                                                  |  24%   40 MB
|===============================================                                                                                                                                                  |  24%   41 MB
|===============================================                                                                                                                                                  |  24%   41 MB
|===============================================                                                                                                                                                  |  24%   41 MB
|===============================================                                                                                                                                                  |  24%   41 MB
|================================================                                                                                                                                                 |  24%   41 MB
|================================================                                                                                                                                                 |  24%   41 MB
|================================================                                                                                                                                                 |  24%   41 MB
|================================================                                                                                                                                                 |  24%   41 MB
|================================================                                                                                                                                                 |  25%   41 MB
|================================================                                                                                                                                                 |  25%   42 MB
|================================================                                                                                                                                                 |  25%   42 MB
|================================================                                                                                                                                                 |  25%   42 MB
|=================================================                                                                                                                                                |  25%   42 MB
|=================================================                                                                                                                                                |  25%   42 MB
|=================================================                                                                                                                                                |  25%   42 MB
|=================================================                                                                                                                                                |  25%   42 MB
|=================================================                                                                                                                                                |  25%   42 MB
|=================================================                                                                                                                                                |  25%   42 MB
|=================================================                                                                                                                                                |  25%   43 MB
|==================================================                                                                                                                                               |  25%   43 MB
|==================================================                                                                                                                                               |  25%   43 MB
|==================================================                                                                                                                                               |  25%   43 MB
|==================================================                                                                                                                                               |  25%   43 MB
|==================================================                                                                                                                                               |  26%   43 MB
|==================================================                                                                                                                                               |  26%   43 MB
|==================================================                                                                                                                                               |  26%   43 MB
|==================================================                                                                                                                                               |  26%   44 MB
|===================================================                                                                                                                                              |  26%   44 MB
|===================================================                                                                                                                                              |  26%   44 MB
|===================================================                                                                                                                                              |  26%   44 MB
|===================================================                                                                                                                                              |  26%   44 MB
|===================================================                                                                                                                                              |  26%   44 MB
|===================================================                                                                                                                                              |  26%   44 MB
|===================================================                                                                                                                                              |  26%   44 MB
|====================================================                                                                                                                                             |  26%   44 MB
|====================================================                                                                                                                                             |  26%   45 MB
|====================================================                                                                                                                                             |  26%   45 MB
|====================================================                                                                                                                                             |  27%   45 MB
|====================================================                                                                                                                                             |  27%   45 MB
|====================================================                                                                                                                                             |  27%   45 MB
|====================================================                                                                                                                                             |  27%   45 MB
|=====================================================                                                                                                                                            |  27%   45 MB
|=====================================================                                                                                                                                            |  27%   45 MB
|=====================================================                                                                                                                                            |  27%   46 MB
|=====================================================                                                                                                                                            |  27%   46 MB
|=====================================================                                                                                                                                            |  27%   46 MB
|=====================================================                                                                                                                                            |  27%   46 MB
|=====================================================                                                                                                                                            |  27%   46 MB
|=====================================================                                                                                                                                            |  27%   46 MB
|======================================================                                                                                                                                           |  27%   46 MB
|======================================================                                                                                                                                           |  27%   46 MB
|======================================================                                                                                                                                           |  28%   46 MB
|======================================================                                                                                                                                           |  28%   47 MB
|======================================================                                                                                                                                           |  28%   47 MB
|======================================================                                                                                                                                           |  28%   47 MB
|======================================================                                                                                                                                           |  28%   47 MB
|=======================================================                                                                                                                                          |  28%   47 MB
|=======================================================                                                                                                                                          |  28%   47 MB
|=======================================================                                                                                                                                          |  28%   47 MB
|=======================================================                                                                                                                                          |  28%   47 MB
|=======================================================                                                                                                                                          |  28%   47 MB
|=======================================================                                                                                                                                          |  28%   48 MB
|=======================================================                                                                                                                                          |  28%   48 MB
|=======================================================                                                                                                                                          |  28%   48 MB
|========================================================                                                                                                                                         |  28%   48 MB
|========================================================                                                                                                                                         |  28%   48 MB
|========================================================                                                                                                                                         |  29%   48 MB
|========================================================                                                                                                                                         |  29%   48 MB
|========================================================                                                                                                                                         |  29%   48 MB
|========================================================                                                                                                                                         |  29%   49 MB
|========================================================                                                                                                                                         |  29%   49 MB
|=========================================================                                                                                                                                        |  29%   49 MB
|=========================================================                                                                                                                                        |  29%   49 MB
|=========================================================                                                                                                                                        |  29%   49 MB
|=========================================================                                                                                                                                        |  29%   49 MB
|=========================================================                                                                                                                                        |  29%   49 MB
|=========================================================                                                                                                                                        |  29%   49 MB
|=========================================================                                                                                                                                        |  29%   49 MB
|=========================================================                                                                                                                                        |  29%   50 MB
|==========================================================                                                                                                                                       |  29%   50 MB
|==========================================================                                                                                                                                       |  30%   50 MB
|==========================================================                                                                                                                                       |  30%   50 MB
|==========================================================                                                                                                                                       |  30%   50 MB
|==========================================================                                                                                                                                       |  30%   50 MB
|==========================================================                                                                                                                                       |  30%   50 MB
|==========================================================                                                                                                                                       |  30%   50 MB
|===========================================================                                                                                                                                      |  30%   50 MB
|===========================================================                                                                                                                                      |  30%   51 MB
|===========================================================                                                                                                                                      |  30%   51 MB
|===========================================================                                                                                                                                      |  30%   51 MB
|===========================================================                                                                                                                                      |  30%   51 MB
|===========================================================                                                                                                                                      |  30%   51 MB
|===========================================================                                                                                                                                      |  30%   51 MB
|============================================================                                                                                                                                     |  30%   51 MB
|============================================================                                                                                                                                     |  30%   51 MB
|============================================================                                                                                                                                     |  31%   52 MB
|============================================================                                                                                                                                     |  31%   52 MB
|============================================================                                                                                                                                     |  31%   52 MB
|============================================================                                                                                                                                     |  31%   52 MB
|============================================================                                                                                                                                     |  31%   52 MB
|============================================================                                                                                                                                     |  31%   52 MB
|=============================================================                                                                                                                                    |  31%   52 MB
|=============================================================                                                                                                                                    |  31%   52 MB
|=============================================================                                                                                                                                    |  31%   52 MB
|=============================================================                                                                                                                                    |  31%   53 MB
|=============================================================                                                                                                                                    |  31%   53 MB
|=============================================================                                                                                                                                    |  31%   53 MB
|=============================================================                                                                                                                                    |  31%   53 MB
|=============================================================                                                                                                                                    |  31%   53 MB
|==============================================================                                                                                                                                   |  32%   53 MB
|==============================================================                                                                                                                                   |  32%   53 MB
|==============================================================                                                                                                                                   |  32%   53 MB
|==============================================================                                                                                                                                   |  32%   53 MB
|==============================================================                                                                                                                                   |  32%   54 MB
|==============================================================                                                                                                                                   |  32%   54 MB
|==============================================================                                                                                                                                   |  32%   54 MB
|===============================================================                                                                                                                                  |  32%   54 MB
|===============================================================                                                                                                                                  |  32%   54 MB
|===============================================================                                                                                                                                  |  32%   54 MB
|===============================================================                                                                                                                                  |  32%   54 MB
|===============================================================                                                                                                                                  |  32%   54 MB
|===============================================================                                                                                                                                  |  32%   55 MB
|===============================================================                                                                                                                                  |  32%   55 MB
|===============================================================                                                                                                                                  |  32%   55 MB
|================================================================                                                                                                                                 |  33%   55 MB
|================================================================                                                                                                                                 |  33%   55 MB
|================================================================                                                                                                                                 |  33%   55 MB
|================================================================                                                                                                                                 |  33%   55 MB
|================================================================                                                                                                                                 |  33%   55 MB
|================================================================                                                                                                                                 |  33%   55 MB
|================================================================                                                                                                                                 |  33%   56 MB
|=================================================================                                                                                                                                |  33%   56 MB
|=================================================================                                                                                                                                |  33%   56 MB
|=================================================================                                                                                                                                |  33%   56 MB
|=================================================================                                                                                                                                |  33%   56 MB
|=================================================================                                                                                                                                |  33%   56 MB
|=================================================================                                                                                                                                |  33%   56 MB
|=================================================================                                                                                                                                |  33%   56 MB
|==================================================================                                                                                                                               |  34%   56 MB
|==================================================================                                                                                                                               |  34%   57 MB
|==================================================================                                                                                                                               |  34%   57 MB
|==================================================================                                                                                                                               |  34%   57 MB
|==================================================================                                                                                                                               |  34%   57 MB
|==================================================================                                                                                                                               |  34%   57 MB
|==================================================================                                                                                                                               |  34%   57 MB
|==================================================================                                                                                                                               |  34%   57 MB
|===================================================================                                                                                                                              |  34%   57 MB
|===================================================================                                                                                                                              |  34%   58 MB
|===================================================================                                                                                                                              |  34%   58 MB
|===================================================================                                                                                                                              |  34%   58 MB
|===================================================================                                                                                                                              |  34%   58 MB
|===================================================================                                                                                                                              |  34%   58 MB
|===================================================================                                                                                                                              |  35%   58 MB
|====================================================================                                                                                                                             |  35%   58 MB
|====================================================================                                                                                                                             |  35%   58 MB
|====================================================================                                                                                                                             |  35%   58 MB
|====================================================================                                                                                                                             |  35%   59 MB
|====================================================================                                                                                                                             |  35%   59 MB
|====================================================================                                                                                                                             |  35%   59 MB
|====================================================================                                                                                                                             |  35%   59 MB
|====================================================================                                                                                                                             |  35%   59 MB
|=====================================================================                                                                                                                            |  35%   59 MB
|=====================================================================                                                                                                                            |  35%   59 MB
|=====================================================================                                                                                                                            |  35%   59 MB
|=====================================================================                                                                                                                            |  35%   59 MB
|=====================================================================                                                                                                                            |  35%   60 MB
|=====================================================================                                                                                                                            |  35%   60 MB
|=====================================================================                                                                                                                            |  36%   60 MB
|======================================================================                                                                                                                           |  36%   60 MB
|======================================================================                                                                                                                           |  36%   60 MB
|======================================================================                                                                                                                           |  36%   60 MB
|======================================================================                                                                                                                           |  36%   60 MB
|======================================================================                                                                                                                           |  36%   60 MB
|======================================================================                                                                                                                           |  36%   61 MB
|======================================================================                                                                                                                           |  36%   61 MB
|======================================================================                                                                                                                           |  36%   61 MB
|=======================================================================                                                                                                                          |  36%   61 MB
|=======================================================================                                                                                                                          |  36%   61 MB
|=======================================================================                                                                                                                          |  36%   61 MB
|=======================================================================                                                                                                                          |  36%   61 MB
|=======================================================================                                                                                                                          |  36%   61 MB
|=======================================================================                                                                                                                          |  36%   61 MB
|=======================================================================                                                                                                                          |  37%   62 MB
|========================================================================                                                                                                                         |  37%   62 MB
|========================================================================                                                                                                                         |  37%   62 MB
|========================================================================                                                                                                                         |  37%   62 MB
|========================================================================                                                                                                                         |  37%   62 MB
|========================================================================                                                                                                                         |  37%   62 MB
|========================================================================                                                                                                                         |  37%   62 MB
|========================================================================                                                                                                                         |  37%   62 MB
|========================================================================                                                                                                                         |  37%   62 MB
|=========================================================================                                                                                                                        |  37%   63 MB
|=========================================================================                                                                                                                        |  37%   63 MB
|=========================================================================                                                                                                                        |  37%   63 MB
|=========================================================================                                                                                                                        |  37%   63 MB
|=========================================================================                                                                                                                        |  37%   63 MB
|=========================================================================                                                                                                                        |  38%   63 MB
|=========================================================================                                                                                                                        |  38%   63 MB
|==========================================================================                                                                                                                       |  38%   63 MB
|==========================================================================                                                                                                                       |  38%   64 MB
|==========================================================================                                                                                                                       |  38%   64 MB
|==========================================================================                                                                                                                       |  38%   64 MB
|==========================================================================                                                                                                                       |  38%   64 MB
|==========================================================================                                                                                                                       |  38%   64 MB
|==========================================================================                                                                                                                       |  38%   64 MB
|===========================================================================                                                                                                                      |  38%   64 MB
|===========================================================================                                                                                                                      |  38%   64 MB
|===========================================================================                                                                                                                      |  38%   64 MB
|===========================================================================                                                                                                                      |  38%   65 MB
|===========================================================================                                                                                                                      |  38%   65 MB
|===========================================================================                                                                                                                      |  39%   65 MB
|===========================================================================                                                                                                                      |  39%   65 MB
|===========================================================================                                                                                                                      |  39%   65 MB
|============================================================================                                                                                                                     |  39%   65 MB
|============================================================================                                                                                                                     |  39%   65 MB
|============================================================================                                                                                                                     |  39%   65 MB
|============================================================================                                                                                                                     |  39%   66 MB
|============================================================================                                                                                                                     |  39%   66 MB
|============================================================================                                                                                                                     |  39%   66 MB
|============================================================================                                                                                                                     |  39%   66 MB
|=============================================================================                                                                                                                    |  39%   66 MB
|=============================================================================                                                                                                                    |  39%   66 MB
|=============================================================================                                                                                                                    |  39%   66 MB
|=============================================================================                                                                                                                    |  39%   66 MB
|=============================================================================                                                                                                                    |  39%   66 MB
|=============================================================================                                                                                                                    |  40%   67 MB
|=============================================================================                                                                                                                    |  40%   67 MB
|=============================================================================                                                                                                                    |  40%   67 MB
|==============================================================================                                                                                                                   |  40%   67 MB
|==============================================================================                                                                                                                   |  40%   67 MB
|==============================================================================                                                                                                                   |  40%   67 MB
|==============================================================================                                                                                                                   |  40%   67 MB
|==============================================================================                                                                                                                   |  40%   67 MB
|==============================================================================                                                                                                                   |  40%   67 MB
|==============================================================================                                                                                                                   |  40%   68 MB
|===============================================================================                                                                                                                  |  40%   68 MB
|===============================================================================                                                                                                                  |  40%   68 MB
|===============================================================================                                                                                                                  |  40%   68 MB
|===============================================================================                                                                                                                  |  40%   68 MB
|===============================================================================                                                                                                                  |  41%   68 MB
|===============================================================================                                                                                                                  |  41%   68 MB
|===============================================================================                                                                                                                  |  41%   68 MB
|===============================================================================                                                                                                                  |  41%   69 MB
|================================================================================                                                                                                                 |  41%   69 MB
|================================================================================                                                                                                                 |  41%   69 MB
|================================================================================                                                                                                                 |  41%   69 MB
|================================================================================                                                                                                                 |  41%   69 MB
|================================================================================                                                                                                                 |  41%   69 MB
|================================================================================                                                                                                                 |  41%   69 MB
|================================================================================                                                                                                                 |  41%   69 MB
|=================================================================================                                                                                                                |  41%   69 MB
|=================================================================================                                                                                                                |  41%   70 MB
|=================================================================================                                                                                                                |  41%   70 MB
|=================================================================================                                                                                                                |  41%   70 MB
|=================================================================================                                                                                                                |  42%   70 MB
|=================================================================================                                                                                                                |  42%   70 MB
|=================================================================================                                                                                                                |  42%   70 MB
|==================================================================================                                                                                                               |  42%   70 MB
|==================================================================================                                                                                                               |  42%   70 MB
|==================================================================================                                                                                                               |  42%   71 MB
|==================================================================================                                                                                                               |  42%   71 MB
|==================================================================================                                                                                                               |  42%   71 MB
|==================================================================================                                                                                                               |  42%   71 MB
|==================================================================================                                                                                                               |  42%   71 MB
|==================================================================================                                                                                                               |  42%   71 MB
|===================================================================================                                                                                                              |  42%   71 MB
|===================================================================================                                                                                                              |  42%   71 MB
|===================================================================================                                                                                                              |  42%   71 MB
|===================================================================================                                                                                                              |  43%   72 MB
|===================================================================================                                                                                                              |  43%   72 MB
|===================================================================================                                                                                                              |  43%   72 MB
|===================================================================================                                                                                                              |  43%   72 MB
|====================================================================================                                                                                                             |  43%   72 MB
|====================================================================================                                                                                                             |  43%   72 MB
|====================================================================================                                                                                                             |  43%   72 MB
|====================================================================================                                                                                                             |  43%   72 MB
|====================================================================================                                                                                                             |  43%   72 MB
|====================================================================================                                                                                                             |  43%   73 MB
|====================================================================================                                                                                                             |  43%   73 MB
|====================================================================================                                                                                                             |  43%   73 MB
|=====================================================================================                                                                                                            |  43%   73 MB
|=====================================================================================                                                                                                            |  43%   73 MB
|=====================================================================================                                                                                                            |  43%   73 MB
|=====================================================================================                                                                                                            |  44%   73 MB
|=====================================================================================                                                                                                            |  44%   73 MB
|=====================================================================================                                                                                                            |  44%   74 MB
|=====================================================================================                                                                                                            |  44%   74 MB
|======================================================================================                                                                                                           |  44%   74 MB
|======================================================================================                                                                                                           |  44%   74 MB
|======================================================================================                                                                                                           |  44%   74 MB
|======================================================================================                                                                                                           |  44%   74 MB
|======================================================================================                                                                                                           |  44%   74 MB
|======================================================================================                                                                                                           |  44%   74 MB
|======================================================================================                                                                                                           |  44%   74 MB
|======================================================================================                                                                                                           |  44%   75 MB
|=======================================================================================                                                                                                          |  44%   75 MB
|=======================================================================================                                                                                                          |  44%   75 MB
|=======================================================================================                                                                                                          |  45%   75 MB
|=======================================================================================                                                                                                          |  45%   75 MB
|=======================================================================================                                                                                                          |  45%   75 MB
|=======================================================================================                                                                                                          |  45%   75 MB
|=======================================================================================                                                                                                          |  45%   75 MB
|=======================================================================================                                                                                                          |  45%   75 MB
|========================================================================================                                                                                                         |  45%   76 MB
|========================================================================================                                                                                                         |  45%   76 MB
|========================================================================================                                                                                                         |  45%   76 MB
|========================================================================================                                                                                                         |  45%   76 MB
|========================================================================================                                                                                                         |  45%   76 MB
|========================================================================================                                                                                                         |  45%   76 MB
|========================================================================================                                                                                                         |  45%   76 MB
|=========================================================================================                                                                                                        |  45%   76 MB
|=========================================================================================                                                                                                        |  45%   77 MB
|=========================================================================================                                                                                                        |  46%   77 MB
|=========================================================================================                                                                                                        |  46%   77 MB
|=========================================================================================                                                                                                        |  46%   77 MB
|=========================================================================================                                                                                                        |  46%   77 MB
|=========================================================================================                                                                                                        |  46%   77 MB
|==========================================================================================                                                                                                       |  46%   77 MB
|==========================================================================================                                                                                                       |  46%   77 MB
|==========================================================================================                                                                                                       |  46%   77 MB
|==========================================================================================                                                                                                       |  46%   78 MB
|==========================================================================================                                                                                                       |  46%   78 MB
|==========================================================================================                                                                                                       |  46%   78 MB
|==========================================================================================                                                                                                       |  46%   78 MB
|==========================================================================================                                                                                                       |  46%   78 MB
|===========================================================================================                                                                                                      |  46%   78 MB
|===========================================================================================                                                                                                      |  47%   78 MB
|===========================================================================================                                                                                                      |  47%   78 MB
|===========================================================================================                                                                                                      |  47%   78 MB
|===========================================================================================                                                                                                      |  47%   79 MB
|===========================================================================================                                                                                                      |  47%   79 MB
|===========================================================================================                                                                                                      |  47%   79 MB
|============================================================================================                                                                                                     |  47%   79 MB
|============================================================================================                                                                                                     |  47%   79 MB
|============================================================================================                                                                                                     |  47%   79 MB
|============================================================================================                                                                                                     |  47%   79 MB
|============================================================================================                                                                                                     |  47%   79 MB
|============================================================================================                                                                                                     |  47%   79 MB
|============================================================================================                                                                                                     |  47%   80 MB
|============================================================================================                                                                                                     |  47%   80 MB
|=============================================================================================                                                                                                    |  47%   80 MB
|=============================================================================================                                                                                                    |  48%   80 MB
|=============================================================================================                                                                                                    |  48%   80 MB
|=============================================================================================                                                                                                    |  48%   80 MB
|=============================================================================================                                                                                                    |  48%   80 MB
|=============================================================================================                                                                                                    |  48%   80 MB
|=============================================================================================                                                                                                    |  48%   80 MB
|=============================================================================================                                                                                                    |  48%   81 MB
|==============================================================================================                                                                                                   |  48%   81 MB
|==============================================================================================                                                                                                   |  48%   81 MB
|==============================================================================================                                                                                                   |  48%   81 MB
|==============================================================================================                                                                                                   |  48%   81 MB
|==============================================================================================                                                                                                   |  48%   81 MB
|==============================================================================================                                                                                                   |  48%   81 MB
|==============================================================================================                                                                                                   |  48%   81 MB
|===============================================================================================                                                                                                  |  48%   82 MB
|===============================================================================================                                                                                                  |  49%   82 MB
|===============================================================================================                                                                                                  |  49%   82 MB
|===============================================================================================                                                                                                  |  49%   82 MB
|===============================================================================================                                                                                                  |  49%   82 MB
|===============================================================================================                                                                                                  |  49%   82 MB
|===============================================================================================                                                                                                  |  49%   82 MB
|===============================================================================================                                                                                                  |  49%   82 MB
|================================================================================================                                                                                                 |  49%   82 MB
|================================================================================================                                                                                                 |  49%   83 MB
|================================================================================================                                                                                                 |  49%   83 MB
|================================================================================================                                                                                                 |  49%   83 MB
|================================================================================================                                                                                                 |  49%   83 MB
|================================================================================================                                                                                                 |  49%   83 MB
|================================================================================================                                                                                                 |  49%   83 MB
|=================================================================================================                                                                                                |  50%   83 MB
|=================================================================================================                                                                                                |  50%   83 MB
|=================================================================================================                                                                                                |  50%   83 MB
|=================================================================================================                                                                                                |  50%   84 MB
|=================================================================================================                                                                                                |  50%   84 MB
|=================================================================================================                                                                                                |  50%   84 MB
|=================================================================================================                                                                                                |  50%   84 MB
|=================================================================================================                                                                                                |  50%   84 MB
|==================================================================================================                                                                                               |  50%   84 MB
|==================================================================================================                                                                                               |  50%   84 MB
|==================================================================================================                                                                                               |  50%   84 MB
|==================================================================================================                                                                                               |  50%   84 MB
|==================================================================================================                                                                                               |  50%   85 MB
|==================================================================================================                                                                                               |  50%   85 MB
|==================================================================================================                                                                                               |  50%   85 MB
|==================================================================================================                                                                                               |  51%   85 MB
|===================================================================================================                                                                                              |  51%   85 MB
|===================================================================================================                                                                                              |  51%   85 MB
|===================================================================================================                                                                                              |  51%   85 MB
|===================================================================================================                                                                                              |  51%   85 MB
|===================================================================================================                                                                                              |  51%   85 MB
|===================================================================================================                                                                                              |  51%   86 MB
|===================================================================================================                                                                                              |  51%   86 MB
|====================================================================================================                                                                                             |  51%   86 MB
|====================================================================================================                                                                                             |  51%   86 MB
|====================================================================================================                                                                                             |  51%   86 MB
|====================================================================================================                                                                                             |  51%   86 MB
|====================================================================================================                                                                                             |  51%   86 MB
|====================================================================================================                                                                                             |  51%   86 MB
|====================================================================================================                                                                                             |  51%   87 MB
|====================================================================================================                                                                                             |  52%   87 MB
|=====================================================================================================                                                                                            |  52%   87 MB
|=====================================================================================================                                                                                            |  52%   87 MB
|=====================================================================================================                                                                                            |  52%   87 MB
|=====================================================================================================                                                                                            |  52%   87 MB
|=====================================================================================================                                                                                            |  52%   87 MB
|=====================================================================================================                                                                                            |  52%   87 MB
|=====================================================================================================                                                                                            |  52%   87 MB
|=====================================================================================================                                                                                            |  52%   88 MB
|======================================================================================================                                                                                           |  52%   88 MB
|======================================================================================================                                                                                           |  52%   88 MB
|======================================================================================================                                                                                           |  52%   88 MB
|======================================================================================================                                                                                           |  52%   88 MB
|======================================================================================================                                                                                           |  52%   88 MB
|======================================================================================================                                                                                           |  52%   88 MB
|======================================================================================================                                                                                           |  53%   88 MB
|=======================================================================================================                                                                                          |  53%   88 MB
|=======================================================================================================                                                                                          |  53%   89 MB
|=======================================================================================================                                                                                          |  53%   89 MB
|=======================================================================================================                                                                                          |  53%   89 MB
|=======================================================================================================                                                                                          |  53%   89 MB
|=======================================================================================================                                                                                          |  53%   89 MB
|=======================================================================================================                                                                                          |  53%   89 MB
|=======================================================================================================                                                                                          |  53%   89 MB
|========================================================================================================                                                                                         |  53%   89 MB
|========================================================================================================                                                                                         |  53%   89 MB
|========================================================================================================                                                                                         |  53%   90 MB
|========================================================================================================                                                                                         |  53%   90 MB
|========================================================================================================                                                                                         |  53%   90 MB
|========================================================================================================                                                                                         |  54%   90 MB
|========================================================================================================                                                                                         |  54%   90 MB
|=========================================================================================================                                                                                        |  54%   90 MB
|=========================================================================================================                                                                                        |  54%   90 MB
|=========================================================================================================                                                                                        |  54%   90 MB
|=========================================================================================================                                                                                        |  54%   91 MB
|=========================================================================================================                                                                                        |  54%   91 MB
|=========================================================================================================                                                                                        |  54%   91 MB
|=========================================================================================================                                                                                        |  54%   91 MB
|==========================================================================================================                                                                                       |  54%   91 MB
|==========================================================================================================                                                                                       |  54%   91 MB
|==========================================================================================================                                                                                       |  54%   91 MB
|==========================================================================================================                                                                                       |  54%   91 MB
|==========================================================================================================                                                                                       |  54%   91 MB
|==========================================================================================================                                                                                       |  55%   92 MB
|==========================================================================================================                                                                                       |  55%   92 MB
|==========================================================================================================                                                                                       |  55%   92 MB
|===========================================================================================================                                                                                      |  55%   92 MB
|===========================================================================================================                                                                                      |  55%   92 MB
|===========================================================================================================                                                                                      |  55%   92 MB
|===========================================================================================================                                                                                      |  55%   92 MB
|===========================================================================================================                                                                                      |  55%   92 MB
|===========================================================================================================                                                                                      |  55%   93 MB
|===========================================================================================================                                                                                      |  55%   93 MB
|============================================================================================================                                                                                     |  55%   93 MB
|============================================================================================================                                                                                     |  55%   93 MB
|============================================================================================================                                                                                     |  55%   93 MB
|============================================================================================================                                                                                     |  55%   93 MB
|============================================================================================================                                                                                     |  55%   93 MB
|============================================================================================================                                                                                     |  56%   93 MB
|============================================================================================================                                                                                     |  56%   93 MB
|=============================================================================================================                                                                                    |  56%   94 MB
|=============================================================================================================                                                                                    |  56%   94 MB
|=============================================================================================================                                                                                    |  56%   94 MB
|=============================================================================================================                                                                                    |  56%   94 MB
|=============================================================================================================                                                                                    |  56%   94 MB
|=============================================================================================================                                                                                    |  56%   94 MB
|=============================================================================================================                                                                                    |  56%   94 MB
|=============================================================================================================                                                                                    |  56%   94 MB
|==============================================================================================================                                                                                   |  56%   95 MB
|==============================================================================================================                                                                                   |  56%   95 MB
|==============================================================================================================                                                                                   |  56%   95 MB
|==============================================================================================================                                                                                   |  56%   95 MB
|==============================================================================================================                                                                                   |  57%   95 MB
|==============================================================================================================                                                                                   |  57%   95 MB
|==============================================================================================================                                                                                   |  57%   95 MB
|===============================================================================================================                                                                                  |  57%   95 MB
|===============================================================================================================                                                                                  |  57%   95 MB
|===============================================================================================================                                                                                  |  57%   96 MB
|===============================================================================================================                                                                                  |  57%   96 MB
|===============================================================================================================                                                                                  |  57%   96 MB
|===============================================================================================================                                                                                  |  57%   96 MB
|===============================================================================================================                                                                                  |  57%   96 MB
|===============================================================================================================                                                                                  |  57%   96 MB
|================================================================================================================                                                                                 |  57%   96 MB
|================================================================================================================                                                                                 |  57%   96 MB
|================================================================================================================                                                                                 |  57%   97 MB
|================================================================================================================                                                                                 |  58%   97 MB
|================================================================================================================                                                                                 |  58%   97 MB
|================================================================================================================                                                                                 |  58%   97 MB
|================================================================================================================                                                                                 |  58%   97 MB
|=================================================================================================================                                                                                |  58%   97 MB
|=================================================================================================================                                                                                |  58%   97 MB
|=================================================================================================================                                                                                |  58%   97 MB
|=================================================================================================================                                                                                |  58%   97 MB
|=================================================================================================================                                                                                |  58%   98 MB
|=================================================================================================================                                                                                |  58%   98 MB
|=================================================================================================================                                                                                |  58%   98 MB
|==================================================================================================================                                                                               |  58%   98 MB
|==================================================================================================================                                                                               |  58%   98 MB
|==================================================================================================================                                                                               |  58%   98 MB
|==================================================================================================================                                                                               |  58%   98 MB
|==================================================================================================================                                                                               |  59%   98 MB
|==================================================================================================================                                                                               |  59%   98 MB
|==================================================================================================================                                                                               |  59%   99 MB
|==================================================================================================================                                                                               |  59%   99 MB
|===================================================================================================================                                                                              |  59%   99 MB
|===================================================================================================================                                                                              |  59%   99 MB
|===================================================================================================================                                                                              |  59%   99 MB
|===================================================================================================================                                                                              |  59%   99 MB
|===================================================================================================================                                                                              |  59%   99 MB
|===================================================================================================================                                                                              |  59%   99 MB
|===================================================================================================================                                                                              |  59%  100 MB
|===================================================================================================================                                                                              |  59%  100 MB
|====================================================================================================================                                                                             |  59%  100 MB
|====================================================================================================================                                                                             |  59%  100 MB
|====================================================================================================================                                                                             |  59%  100 MB
|====================================================================================================================                                                                             |  60%  100 MB
|====================================================================================================================                                                                             |  60%  100 MB
|====================================================================================================================                                                                             |  60%  100 MB
|====================================================================================================================                                                                             |  60%  100 MB
|=====================================================================================================================                                                                            |  60%  101 MB
|=====================================================================================================================                                                                            |  60%  101 MB
|=====================================================================================================================                                                                            |  60%  101 MB
|=====================================================================================================================                                                                            |  60%  101 MB
|=====================================================================================================================                                                                            |  60%  101 MB
|=====================================================================================================================                                                                            |  60%  101 MB
|=====================================================================================================================                                                                            |  60%  101 MB
|======================================================================================================================                                                                           |  60%  101 MB
|======================================================================================================================                                                                           |  60%  101 MB
|======================================================================================================================                                                                           |  60%  102 MB
|======================================================================================================================                                                                           |  61%  102 MB
|======================================================================================================================                                                                           |  61%  102 MB
|======================================================================================================================                                                                           |  61%  102 MB
|======================================================================================================================                                                                           |  61%  102 MB
|======================================================================================================================                                                                           |  61%  102 MB
|=======================================================================================================================                                                                          |  61%  102 MB
|=======================================================================================================================                                                                          |  61%  102 MB
|=======================================================================================================================                                                                          |  61%  103 MB
|=======================================================================================================================                                                                          |  61%  103 MB
|=======================================================================================================================                                                                          |  61%  103 MB
|=======================================================================================================================                                                                          |  61%  103 MB
|=======================================================================================================================                                                                          |  61%  103 MB
|========================================================================================================================                                                                         |  61%  103 MB
|========================================================================================================================                                                                         |  61%  103 MB
|========================================================================================================================                                                                         |  62%  103 MB
|========================================================================================================================                                                                         |  62%  103 MB
|========================================================================================================================                                                                         |  62%  104 MB
|========================================================================================================================                                                                         |  62%  104 MB
|========================================================================================================================                                                                         |  62%  104 MB
|========================================================================================================================                                                                         |  62%  104 MB
|=========================================================================================================================                                                                        |  62%  104 MB
|=========================================================================================================================                                                                        |  62%  104 MB
|=========================================================================================================================                                                                        |  62%  104 MB
|=========================================================================================================================                                                                        |  62%  104 MB
|=========================================================================================================================                                                                        |  62%  104 MB
|=========================================================================================================================                                                                        |  62%  105 MB
|=========================================================================================================================                                                                        |  62%  105 MB
|==========================================================================================================================                                                                       |  62%  105 MB
|==========================================================================================================================                                                                       |  62%  105 MB
|==========================================================================================================================                                                                       |  63%  105 MB
|==========================================================================================================================                                                                       |  63%  105 MB
|==========================================================================================================================                                                                       |  63%  105 MB
|==========================================================================================================================                                                                       |  63%  105 MB
|==========================================================================================================================                                                                       |  63%  106 MB
|==========================================================================================================================                                                                       |  63%  106 MB
|===========================================================================================================================                                                                      |  63%  106 MB
|===========================================================================================================================                                                                      |  63%  106 MB
|===========================================================================================================================                                                                      |  63%  106 MB
|===========================================================================================================================                                                                      |  63%  106 MB
|===========================================================================================================================                                                                      |  63%  106 MB
|===========================================================================================================================                                                                      |  63%  106 MB
|===========================================================================================================================                                                                      |  63%  106 MB
|============================================================================================================================                                                                     |  63%  107 MB
|============================================================================================================================                                                                     |  64%  107 MB
|============================================================================================================================                                                                     |  64%  107 MB
|============================================================================================================================                                                                     |  64%  107 MB
|============================================================================================================================                                                                     |  64%  107 MB
|============================================================================================================================                                                                     |  64%  107 MB
|============================================================================================================================                                                                     |  64%  107 MB
|============================================================================================================================                                                                     |  64%  107 MB
|=============================================================================================================================                                                                    |  64%  107 MB
|=============================================================================================================================                                                                    |  64%  108 MB
|=============================================================================================================================                                                                    |  64%  108 MB
|=============================================================================================================================                                                                    |  64%  108 MB
|=============================================================================================================================                                                                    |  64%  108 MB
|=============================================================================================================================                                                                    |  64%  108 MB
|=============================================================================================================================                                                                    |  64%  108 MB
|==============================================================================================================================                                                                   |  64%  108 MB
|==============================================================================================================================                                                                   |  65%  108 MB
|==============================================================================================================================                                                                   |  65%  109 MB
|==============================================================================================================================                                                                   |  65%  109 MB
|==============================================================================================================================                                                                   |  65%  109 MB
|==============================================================================================================================                                                                   |  65%  109 MB
|==============================================================================================================================                                                                   |  65%  109 MB
|==============================================================================================================================                                                                   |  65%  109 MB
|===============================================================================================================================                                                                  |  65%  109 MB
|===============================================================================================================================                                                                  |  65%  109 MB
|===============================================================================================================================                                                                  |  65%  109 MB
|===============================================================================================================================                                                                  |  65%  110 MB
|===============================================================================================================================                                                                  |  65%  110 MB
|===============================================================================================================================                                                                  |  65%  110 MB
|===============================================================================================================================                                                                  |  65%  110 MB
|================================================================================================================================                                                                 |  65%  110 MB
|================================================================================================================================                                                                 |  66%  110 MB
|================================================================================================================================                                                                 |  66%  110 MB
|================================================================================================================================                                                                 |  66%  110 MB
|================================================================================================================================                                                                 |  66%  110 MB
|================================================================================================================================                                                                 |  66%  111 MB
|================================================================================================================================                                                                 |  66%  111 MB
|================================================================================================================================                                                                 |  66%  111 MB
|=================================================================================================================================                                                                |  66%  111 MB
|=================================================================================================================================                                                                |  66%  111 MB
|=================================================================================================================================                                                                |  66%  111 MB
|=================================================================================================================================                                                                |  66%  111 MB
|=================================================================================================================================                                                                |  66%  111 MB
|=================================================================================================================================                                                                |  66%  111 MB
|=================================================================================================================================                                                                |  66%  112 MB
|=================================================================================================================================                                                                |  66%  112 MB
|==================================================================================================================================                                                               |  67%  112 MB
|==================================================================================================================================                                                               |  67%  112 MB
|==================================================================================================================================                                                               |  67%  112 MB
|==================================================================================================================================                                                               |  67%  112 MB
|==================================================================================================================================                                                               |  67%  112 MB
|==================================================================================================================================                                                               |  67%  112 MB
|==================================================================================================================================                                                               |  67%  113 MB
|===================================================================================================================================                                                              |  67%  113 MB
|===================================================================================================================================                                                              |  67%  113 MB
|===================================================================================================================================                                                              |  67%  113 MB
|===================================================================================================================================                                                              |  67%  113 MB
|===================================================================================================================================                                                              |  67%  113 MB
|===================================================================================================================================                                                              |  67%  113 MB
|===================================================================================================================================                                                              |  68%  113 MB
|====================================================================================================================================                                                             |  68%  114 MB
|====================================================================================================================================                                                             |  68%  114 MB
|====================================================================================================================================                                                             |  68%  114 MB
|====================================================================================================================================                                                             |  68%  114 MB
|====================================================================================================================================                                                             |  68%  114 MB
|====================================================================================================================================                                                             |  68%  114 MB
|====================================================================================================================================                                                             |  68%  114 MB
|=====================================================================================================================================                                                            |  68%  114 MB
|=====================================================================================================================================                                                            |  68%  115 MB
|=====================================================================================================================================                                                            |  68%  115 MB
|=====================================================================================================================================                                                            |  68%  115 MB
|=====================================================================================================================================                                                            |  68%  115 MB
|=====================================================================================================================================                                                            |  68%  115 MB
|=====================================================================================================================================                                                            |  69%  115 MB
|======================================================================================================================================                                                           |  69%  115 MB
|======================================================================================================================================                                                           |  69%  115 MB
|======================================================================================================================================                                                           |  69%  115 MB
|======================================================================================================================================                                                           |  69%  116 MB
|======================================================================================================================================                                                           |  69%  116 MB
|======================================================================================================================================                                                           |  69%  116 MB
|======================================================================================================================================                                                           |  69%  116 MB
|======================================================================================================================================                                                           |  69%  116 MB
|=======================================================================================================================================                                                          |  69%  116 MB
|=======================================================================================================================================                                                          |  69%  116 MB
|=======================================================================================================================================                                                          |  69%  116 MB
|=======================================================================================================================================                                                          |  69%  116 MB
|=======================================================================================================================================                                                          |  69%  117 MB
|=======================================================================================================================================                                                          |  69%  117 MB
|=======================================================================================================================================                                                          |  70%  117 MB
|========================================================================================================================================                                                         |  70%  117 MB
|========================================================================================================================================                                                         |  70%  117 MB
|========================================================================================================================================                                                         |  70%  117 MB
|========================================================================================================================================                                                         |  70%  117 MB
|========================================================================================================================================                                                         |  70%  117 MB
|========================================================================================================================================                                                         |  70%  117 MB
|========================================================================================================================================                                                         |  70%  118 MB
|========================================================================================================================================                                                         |  70%  118 MB
|=========================================================================================================================================                                                        |  70%  118 MB
|=========================================================================================================================================                                                        |  70%  118 MB
|=========================================================================================================================================                                                        |  70%  118 MB
|=========================================================================================================================================                                                        |  70%  118 MB
|=========================================================================================================================================                                                        |  70%  118 MB
|=========================================================================================================================================                                                        |  70%  118 MB
|=========================================================================================================================================                                                        |  71%  119 MB
|=========================================================================================================================================                                                        |  71%  119 MB
|==========================================================================================================================================                                                       |  71%  119 MB
|==========================================================================================================================================                                                       |  71%  119 MB
|==========================================================================================================================================                                                       |  71%  119 MB
|==========================================================================================================================================                                                       |  71%  119 MB
|==========================================================================================================================================                                                       |  71%  119 MB
|==========================================================================================================================================                                                       |  71%  119 MB
|==========================================================================================================================================                                                       |  71%  119 MB
|===========================================================================================================================================                                                      |  71%  120 MB
|===========================================================================================================================================                                                      |  71%  120 MB
|===========================================================================================================================================                                                      |  71%  120 MB
|===========================================================================================================================================                                                      |  71%  120 MB
|===========================================================================================================================================                                                      |  71%  120 MB
|===========================================================================================================================================                                                      |  72%  120 MB
|===========================================================================================================================================                                                      |  72%  120 MB
|===========================================================================================================================================                                                      |  72%  120 MB
|============================================================================================================================================                                                     |  72%  120 MB
|============================================================================================================================================                                                     |  72%  121 MB
|============================================================================================================================================                                                     |  72%  121 MB
|============================================================================================================================================                                                     |  72%  121 MB
|============================================================================================================================================                                                     |  72%  121 MB
|============================================================================================================================================                                                     |  72%  121 MB
|============================================================================================================================================                                                     |  72%  121 MB
|=============================================================================================================================================                                                    |  72%  121 MB
|=============================================================================================================================================                                                    |  72%  121 MB
|=============================================================================================================================================                                                    |  72%  121 MB
|=============================================================================================================================================                                                    |  72%  122 MB
|=============================================================================================================================================                                                    |  72%  122 MB
|=============================================================================================================================================                                                    |  73%  122 MB
|=============================================================================================================================================                                                    |  73%  122 MB
|=============================================================================================================================================                                                    |  73%  122 MB
|==============================================================================================================================================                                                   |  73%  122 MB
|==============================================================================================================================================                                                   |  73%  122 MB
|==============================================================================================================================================                                                   |  73%  122 MB
|==============================================================================================================================================                                                   |  73%  122 MB
|==============================================================================================================================================                                                   |  73%  123 MB
|==============================================================================================================================================                                                   |  73%  123 MB
|==============================================================================================================================================                                                   |  73%  123 MB
|===============================================================================================================================================                                                  |  73%  123 MB
|===============================================================================================================================================                                                  |  73%  123 MB
|===============================================================================================================================================                                                  |  73%  123 MB
|===============================================================================================================================================                                                  |  73%  123 MB
|===============================================================================================================================================                                                  |  73%  123 MB
|===============================================================================================================================================                                                  |  74%  123 MB
|===============================================================================================================================================                                                  |  74%  124 MB
|===============================================================================================================================================                                                  |  74%  124 MB
|================================================================================================================================================                                                 |  74%  124 MB
|================================================================================================================================================                                                 |  74%  124 MB
|================================================================================================================================================                                                 |  74%  124 MB
|================================================================================================================================================                                                 |  74%  124 MB
|================================================================================================================================================                                                 |  74%  124 MB
|================================================================================================================================================                                                 |  74%  124 MB
|================================================================================================================================================                                                 |  74%  124 MB
|================================================================================================================================================                                                 |  74%  125 MB
|=================================================================================================================================================                                                |  74%  125 MB
|=================================================================================================================================================                                                |  74%  125 MB
|=================================================================================================================================================                                                |  74%  125 MB
|=================================================================================================================================================                                                |  74%  125 MB
|=================================================================================================================================================                                                |  75%  125 MB
|=================================================================================================================================================                                                |  75%  125 MB
|=================================================================================================================================================                                                |  75%  125 MB
|=================================================================================================================================================                                                |  75%  125 MB
|==================================================================================================================================================                                               |  75%  126 MB
|==================================================================================================================================================                                               |  75%  126 MB
|==================================================================================================================================================                                               |  75%  126 MB
|==================================================================================================================================================                                               |  75%  126 MB
|==================================================================================================================================================                                               |  75%  126 MB
|==================================================================================================================================================                                               |  75%  126 MB
|==================================================================================================================================================                                               |  75%  126 MB
|==================================================================================================================================================                                               |  75%  126 MB
|===================================================================================================================================================                                              |  75%  126 MB
|===================================================================================================================================================                                              |  75%  127 MB
|===================================================================================================================================================                                              |  75%  127 MB
|===================================================================================================================================================                                              |  76%  127 MB
|===================================================================================================================================================                                              |  76%  127 MB
|===================================================================================================================================================                                              |  76%  127 MB
|===================================================================================================================================================                                              |  76%  127 MB
|====================================================================================================================================================                                             |  76%  127 MB
|====================================================================================================================================================                                             |  76%  127 MB
|====================================================================================================================================================                                             |  76%  128 MB
|====================================================================================================================================================                                             |  76%  128 MB
|====================================================================================================================================================                                             |  76%  128 MB
|====================================================================================================================================================                                             |  76%  128 MB
|====================================================================================================================================================                                             |  76%  128 MB
|=====================================================================================================================================================                                            |  76%  128 MB
|=====================================================================================================================================================                                            |  76%  128 MB
|=====================================================================================================================================================                                            |  76%  128 MB
|=====================================================================================================================================================                                            |  77%  128 MB
|=====================================================================================================================================================                                            |  77%  129 MB
|=====================================================================================================================================================                                            |  77%  129 MB
|=====================================================================================================================================================                                            |  77%  129 MB
|=====================================================================================================================================================                                            |  77%  129 MB
|======================================================================================================================================================                                           |  77%  129 MB
|======================================================================================================================================================                                           |  77%  129 MB
|======================================================================================================================================================                                           |  77%  129 MB
|======================================================================================================================================================                                           |  77%  129 MB
|======================================================================================================================================================                                           |  77%  129 MB
|======================================================================================================================================================                                           |  77%  130 MB
|======================================================================================================================================================                                           |  77%  130 MB
|======================================================================================================================================================                                           |  77%  130 MB
|=======================================================================================================================================================                                          |  77%  130 MB
|=======================================================================================================================================================                                          |  77%  130 MB
|=======================================================================================================================================================                                          |  78%  130 MB
|=======================================================================================================================================================                                          |  78%  130 MB
|=======================================================================================================================================================                                          |  78%  130 MB
|=======================================================================================================================================================                                          |  78%  130 MB
|=======================================================================================================================================================                                          |  78%  131 MB
|=======================================================================================================================================================                                          |  78%  131 MB
|========================================================================================================================================================                                         |  78%  131 MB
|========================================================================================================================================================                                         |  78%  131 MB
|========================================================================================================================================================                                         |  78%  131 MB
|========================================================================================================================================================                                         |  78%  131 MB
|========================================================================================================================================================                                         |  78%  131 MB
|========================================================================================================================================================                                         |  78%  131 MB
|========================================================================================================================================================                                         |  78%  131 MB
|=========================================================================================================================================================                                        |  78%  132 MB
|=========================================================================================================================================================                                        |  78%  132 MB
|=========================================================================================================================================================                                        |  79%  132 MB
|=========================================================================================================================================================                                        |  79%  132 MB
|=========================================================================================================================================================                                        |  79%  132 MB
|=========================================================================================================================================================                                        |  79%  132 MB
|=========================================================================================================================================================                                        |  79%  132 MB
|=========================================================================================================================================================                                        |  79%  132 MB
|==========================================================================================================================================================                                       |  79%  133 MB
|==========================================================================================================================================================                                       |  79%  133 MB
|==========================================================================================================================================================                                       |  79%  133 MB
|==========================================================================================================================================================                                       |  79%  133 MB
|==========================================================================================================================================================                                       |  79%  133 MB
|==========================================================================================================================================================                                       |  79%  133 MB
|==========================================================================================================================================================                                       |  79%  133 MB
|===========================================================================================================================================================                                      |  79%  133 MB
|===========================================================================================================================================================                                      |  79%  133 MB
|===========================================================================================================================================================                                      |  80%  134 MB
|===========================================================================================================================================================                                      |  80%  134 MB
|===========================================================================================================================================================                                      |  80%  134 MB
|===========================================================================================================================================================                                      |  80%  134 MB
|===========================================================================================================================================================                                      |  80%  134 MB
|===========================================================================================================================================================                                      |  80%  134 MB
|============================================================================================================================================================                                     |  80%  134 MB
|============================================================================================================================================================                                     |  80%  134 MB
|============================================================================================================================================================                                     |  80%  134 MB
|============================================================================================================================================================                                     |  80%  135 MB
|============================================================================================================================================================                                     |  80%  135 MB
|============================================================================================================================================================                                     |  80%  135 MB
|============================================================================================================================================================                                     |  80%  135 MB
|=============================================================================================================================================================                                    |  80%  135 MB
|=============================================================================================================================================================                                    |  81%  135 MB
|=============================================================================================================================================================                                    |  81%  135 MB
|=============================================================================================================================================================                                    |  81%  135 MB
|=============================================================================================================================================================                                    |  81%  136 MB
|=============================================================================================================================================================                                    |  81%  136 MB
|=============================================================================================================================================================                                    |  81%  136 MB
|=============================================================================================================================================================                                    |  81%  136 MB
|==============================================================================================================================================================                                   |  81%  136 MB
|==============================================================================================================================================================                                   |  81%  136 MB
|==============================================================================================================================================================                                   |  81%  136 MB
|==============================================================================================================================================================                                   |  81%  136 MB
|==============================================================================================================================================================                                   |  81%  136 MB
|==============================================================================================================================================================                                   |  81%  137 MB
|==============================================================================================================================================================                                   |  81%  137 MB
|===============================================================================================================================================================                                  |  81%  137 MB
|===============================================================================================================================================================                                  |  82%  137 MB
|===============================================================================================================================================================                                  |  82%  137 MB
|===============================================================================================================================================================                                  |  82%  137 MB
|===============================================================================================================================================================                                  |  82%  137 MB
|===============================================================================================================================================================                                  |  82%  137 MB
|===============================================================================================================================================================                                  |  82%  137 MB
|===============================================================================================================================================================                                  |  82%  138 MB
|================================================================================================================================================================                                 |  82%  138 MB
|================================================================================================================================================================                                 |  82%  138 MB
|================================================================================================================================================================                                 |  82%  138 MB
|================================================================================================================================================================                                 |  82%  138 MB
|================================================================================================================================================================                                 |  82%  138 MB
|================================================================================================================================================================                                 |  82%  138 MB
|================================================================================================================================================================                                 |  82%  138 MB
|=================================================================================================================================================================                                |  82%  138 MB
|=================================================================================================================================================================                                |  83%  139 MB
|=================================================================================================================================================================                                |  83%  139 MB
|=================================================================================================================================================================                                |  83%  139 MB
|=================================================================================================================================================================                                |  83%  139 MB
|=================================================================================================================================================================                                |  83%  139 MB
|=================================================================================================================================================================                                |  83%  139 MB
|=================================================================================================================================================================                                |  83%  139 MB
|==================================================================================================================================================================                               |  83%  139 MB
|==================================================================================================================================================================                               |  83%  140 MB
|==================================================================================================================================================================                               |  83%  140 MB
|==================================================================================================================================================================                               |  83%  140 MB
|==================================================================================================================================================================                               |  83%  140 MB
|==================================================================================================================================================================                               |  83%  140 MB
|==================================================================================================================================================================                               |  83%  140 MB
|===================================================================================================================================================================                              |  84%  140 MB
|===================================================================================================================================================================                              |  84%  140 MB
|===================================================================================================================================================================                              |  84%  140 MB
|===================================================================================================================================================================                              |  84%  141 MB
|===================================================================================================================================================================                              |  84%  141 MB
|===================================================================================================================================================================                              |  84%  141 MB
|===================================================================================================================================================================                              |  84%  141 MB
|===================================================================================================================================================================                              |  84%  141 MB
|====================================================================================================================================================================                             |  84%  141 MB
|====================================================================================================================================================================                             |  84%  141 MB
|====================================================================================================================================================================                             |  84%  141 MB
|====================================================================================================================================================================                             |  84%  142 MB
|====================================================================================================================================================================                             |  84%  142 MB
|====================================================================================================================================================================                             |  84%  142 MB
|====================================================================================================================================================================                             |  85%  142 MB
|=====================================================================================================================================================================                            |  85%  142 MB
|=====================================================================================================================================================================                            |  85%  142 MB
|=====================================================================================================================================================================                            |  85%  142 MB
|=====================================================================================================================================================================                            |  85%  142 MB
|=====================================================================================================================================================================                            |  85%  142 MB
|=====================================================================================================================================================================                            |  85%  143 MB
|=====================================================================================================================================================================                            |  85%  143 MB
|======================================================================================================================================================================                           |  85%  143 MB
|======================================================================================================================================================================                           |  85%  143 MB
|======================================================================================================================================================================                           |  85%  143 MB
|======================================================================================================================================================================                           |  85%  143 MB
|======================================================================================================================================================================                           |  85%  143 MB
|======================================================================================================================================================================                           |  85%  143 MB
|======================================================================================================================================================================                           |  85%  143 MB
|======================================================================================================================================================================                           |  86%  144 MB
|=======================================================================================================================================================================                          |  86%  144 MB
|=======================================================================================================================================================================                          |  86%  144 MB
|=======================================================================================================================================================================                          |  86%  144 MB
|=======================================================================================================================================================================                          |  86%  144 MB
|=======================================================================================================================================================================                          |  86%  144 MB
|=======================================================================================================================================================================                          |  86%  144 MB
|=======================================================================================================================================================================                          |  86%  144 MB
|========================================================================================================================================================================                         |  86%  145 MB
|========================================================================================================================================================================                         |  86%  145 MB
|========================================================================================================================================================================                         |  86%  145 MB
|========================================================================================================================================================================                         |  86%  145 MB
|========================================================================================================================================================================                         |  86%  145 MB
|========================================================================================================================================================================                         |  86%  145 MB
|========================================================================================================================================================================                         |  87%  145 MB
|========================================================================================================================================================================                         |  87%  145 MB
|=========================================================================================================================================================================                        |  87%  145 MB
|=========================================================================================================================================================================                        |  87%  146 MB
|=========================================================================================================================================================================                        |  87%  146 MB
|=========================================================================================================================================================================                        |  87%  146 MB
|=========================================================================================================================================================================                        |  87%  146 MB
|=========================================================================================================================================================================                        |  87%  146 MB
|=========================================================================================================================================================================                        |  87%  146 MB
|==========================================================================================================================================================================                       |  87%  146 MB
|==========================================================================================================================================================================                       |  87%  146 MB
|==========================================================================================================================================================================                       |  87%  147 MB
|==========================================================================================================================================================================                       |  87%  147 MB
|==========================================================================================================================================================================                       |  87%  147 MB
|==========================================================================================================================================================================                       |  88%  147 MB
|==========================================================================================================================================================================                       |  88%  147 MB
|==========================================================================================================================================================================                       |  88%  147 MB
|===========================================================================================================================================================================                      |  88%  147 MB
|===========================================================================================================================================================================                      |  88%  147 MB
|===========================================================================================================================================================================                      |  88%  147 MB
|===========================================================================================================================================================================                      |  88%  148 MB
|===========================================================================================================================================================================                      |  88%  148 MB
|===========================================================================================================================================================================                      |  88%  148 MB
|===========================================================================================================================================================================                      |  88%  148 MB
|============================================================================================================================================================================                     |  88%  148 MB
|============================================================================================================================================================================                     |  88%  148 MB
|============================================================================================================================================================================                     |  88%  148 MB
|============================================================================================================================================================================                     |  88%  148 MB
|============================================================================================================================================================================                     |  88%  148 MB
|============================================================================================================================================================================                     |  89%  149 MB
|============================================================================================================================================================================                     |  89%  149 MB
|============================================================================================================================================================================                     |  89%  149 MB
|=============================================================================================================================================================================                    |  89%  149 MB
|=============================================================================================================================================================================                    |  89%  149 MB
|=============================================================================================================================================================================                    |  89%  149 MB
|=============================================================================================================================================================================                    |  89%  149 MB
|=============================================================================================================================================================================                    |  89%  149 MB
|=============================================================================================================================================================================                    |  89%  150 MB
|=============================================================================================================================================================================                    |  89%  150 MB
|==============================================================================================================================================================================                   |  89%  150 MB
|==============================================================================================================================================================================                   |  89%  150 MB
|==============================================================================================================================================================================                   |  89%  150 MB
|==============================================================================================================================================================================                   |  89%  150 MB
|==============================================================================================================================================================================                   |  90%  150 MB
|==============================================================================================================================================================================                   |  90%  150 MB
|==============================================================================================================================================================================                   |  90%  150 MB
|===============================================================================================================================================================================                  |  90%  151 MB
|===============================================================================================================================================================================                  |  90%  151 MB
|===============================================================================================================================================================================                  |  90%  151 MB
|===============================================================================================================================================================================                  |  90%  151 MB
|===============================================================================================================================================================================                  |  90%  151 MB
|===============================================================================================================================================================================                  |  90%  151 MB
|===============================================================================================================================================================================                  |  90%  151 MB
|================================================================================================================================================================================                 |  90%  151 MB
|================================================================================================================================================================================                 |  90%  152 MB
|================================================================================================================================================================================                 |  90%  152 MB
|================================================================================================================================================================================                 |  90%  152 MB
|================================================================================================================================================================================                 |  91%  152 MB
|================================================================================================================================================================================                 |  91%  152 MB
|================================================================================================================================================================================                 |  91%  152 MB
|================================================================================================================================================================================                 |  91%  152 MB
|=================================================================================================================================================================================                |  91%  152 MB
|=================================================================================================================================================================================                |  91%  152 MB
|=================================================================================================================================================================================                |  91%  153 MB
|=================================================================================================================================================================================                |  91%  153 MB
|=================================================================================================================================================================================                |  91%  153 MB
|=================================================================================================================================================================================                |  91%  153 MB
|=================================================================================================================================================================================                |  91%  153 MB
|==================================================================================================================================================================================               |  91%  153 MB
|==================================================================================================================================================================================               |  91%  153 MB
|==================================================================================================================================================================================               |  91%  153 MB
|==================================================================================================================================================================================               |  91%  153 MB
|==================================================================================================================================================================================               |  92%  154 MB
|==================================================================================================================================================================================               |  92%  154 MB
|==================================================================================================================================================================================               |  92%  154 MB
|==================================================================================================================================================================================               |  92%  154 MB
|===================================================================================================================================================================================              |  92%  154 MB
|===================================================================================================================================================================================              |  92%  154 MB
|===================================================================================================================================================================================              |  92%  154 MB
|===================================================================================================================================================================================              |  92%  154 MB
|===================================================================================================================================================================================              |  92%  155 MB
|===================================================================================================================================================================================              |  92%  155 MB
|===================================================================================================================================================================================              |  92%  155 MB
|====================================================================================================================================================================================             |  92%  155 MB
|====================================================================================================================================================================================             |  92%  155 MB
|====================================================================================================================================================================================             |  92%  155 MB
|====================================================================================================================================================================================             |  92%  155 MB
|====================================================================================================================================================================================             |  93%  155 MB
|====================================================================================================================================================================================             |  93%  155 MB
|====================================================================================================================================================================================             |  93%  156 MB
|====================================================================================================================================================================================             |  93%  156 MB
|=====================================================================================================================================================================================            |  93%  156 MB
|=====================================================================================================================================================================================            |  93%  156 MB
|=====================================================================================================================================================================================            |  93%  156 MB
|=====================================================================================================================================================================================            |  93%  156 MB
|=====================================================================================================================================================================================            |  93%  156 MB
|=====================================================================================================================================================================================            |  93%  156 MB
|=====================================================================================================================================================================================            |  93%  156 MB
|======================================================================================================================================================================================           |  93%  157 MB
|======================================================================================================================================================================================           |  93%  157 MB
|======================================================================================================================================================================================           |  93%  157 MB
|======================================================================================================================================================================================           |  94%  157 MB
|======================================================================================================================================================================================           |  94%  157 MB
|======================================================================================================================================================================================           |  94%  157 MB
|======================================================================================================================================================================================           |  94%  157 MB
|======================================================================================================================================================================================           |  94%  157 MB
|=======================================================================================================================================================================================          |  94%  158 MB
|=======================================================================================================================================================================================          |  94%  158 MB
|=======================================================================================================================================================================================          |  94%  158 MB
|=======================================================================================================================================================================================          |  94%  158 MB
|=======================================================================================================================================================================================          |  94%  158 MB
|=======================================================================================================================================================================================          |  94%  158 MB
|=======================================================================================================================================================================================          |  94%  158 MB
|========================================================================================================================================================================================         |  94%  158 MB
|========================================================================================================================================================================================         |  94%  158 MB
|========================================================================================================================================================================================         |  94%  159 MB
|========================================================================================================================================================================================         |  95%  159 MB
|========================================================================================================================================================================================         |  95%  159 MB
|========================================================================================================================================================================================         |  95%  159 MB
|========================================================================================================================================================================================         |  95%  159 MB
|========================================================================================================================================================================================         |  95%  159 MB
|=========================================================================================================================================================================================        |  95%  159 MB
|=========================================================================================================================================================================================        |  95%  159 MB
|=========================================================================================================================================================================================        |  95%  160 MB
|=========================================================================================================================================================================================        |  95%  160 MB
|=========================================================================================================================================================================================        |  95%  160 MB
|=========================================================================================================================================================================================        |  95%  160 MB
|=========================================================================================================================================================================================        |  95%  160 MB
|==========================================================================================================================================================================================       |  95%  160 MB
|==========================================================================================================================================================================================       |  95%  160 MB
|==========================================================================================================================================================================================       |  96%  160 MB
|==========================================================================================================================================================================================       |  96%  160 MB
|==========================================================================================================================================================================================       |  96%  161 MB
|==========================================================================================================================================================================================       |  96%  161 MB
|==========================================================================================================================================================================================       |  96%  161 MB
|==========================================================================================================================================================================================       |  96%  161 MB
|===========================================================================================================================================================================================      |  96%  161 MB
|===========================================================================================================================================================================================      |  96%  161 MB
|===========================================================================================================================================================================================      |  96%  161 MB
|===========================================================================================================================================================================================      |  96%  161 MB
|===========================================================================================================================================================================================      |  96%  162 MB
|===========================================================================================================================================================================================      |  96%  162 MB
|===========================================================================================================================================================================================      |  96%  162 MB
|============================================================================================================================================================================================     |  96%  162 MB
|============================================================================================================================================================================================     |  97%  162 MB
|============================================================================================================================================================================================     |  97%  162 MB
|============================================================================================================================================================================================     |  97%  162 MB
|============================================================================================================================================================================================     |  97%  162 MB
|============================================================================================================================================================================================     |  97%  162 MB
|============================================================================================================================================================================================     |  97%  163 MB
|============================================================================================================================================================================================     |  97%  163 MB
|=============================================================================================================================================================================================    |  97%  163 MB
|=============================================================================================================================================================================================    |  97%  163 MB
|=============================================================================================================================================================================================    |  97%  163 MB
|=============================================================================================================================================================================================    |  97%  163 MB
|=============================================================================================================================================================================================    |  97%  163 MB
|=============================================================================================================================================================================================    |  97%  163 MB
|=============================================================================================================================================================================================    |  97%  163 MB
|=============================================================================================================================================================================================    |  97%  163 MB
|==============================================================================================================================================================================================   |  98%  164 MB
|==============================================================================================================================================================================================   |  98%  164 MB
|==============================================================================================================================================================================================   |  98%  164 MB
|==============================================================================================================================================================================================   |  98%  164 MB
|==============================================================================================================================================================================================   |  98%  164 MB
|==============================================================================================================================================================================================   |  98%  164 MB
|==============================================================================================================================================================================================   |  98%  164 MB
|===============================================================================================================================================================================================  |  98%  164 MB
|===============================================================================================================================================================================================  |  98%  165 MB
|===============================================================================================================================================================================================  |  98%  165 MB
|===============================================================================================================================================================================================  |  98%  165 MB
|===============================================================================================================================================================================================  |  98%  165 MB
|===============================================================================================================================================================================================  |  98%  165 MB
|===============================================================================================================================================================================================  |  98%  165 MB
|================================================================================================================================================================================================ |  98%  165 MB
|================================================================================================================================================================================================ |  99%  165 MB
|================================================================================================================================================================================================ |  99%  165 MB
|================================================================================================================================================================================================ |  99%  166 MB
|================================================================================================================================================================================================ |  99%  166 MB
|================================================================================================================================================================================================ |  99%  166 MB
|================================================================================================================================================================================================ |  99%  166 MB
|================================================================================================================================================================================================ |  99%  166 MB
|=================================================================================================================================================================================================|  99%  166 MB
|=================================================================================================================================================================================================|  99%  166 MB
|=================================================================================================================================================================================================|  99%  166 MB
|=================================================================================================================================================================================================|  99%  167 MB
|=================================================================================================================================================================================================|  99%  167 MB
|=================================================================================================================================================================================================|  99%  167 MB
|=================================================================================================================================================================================================|  99%  167 MB
|==================================================================================================================================================================================================| 100%  167 MB

number of columns of result is not a multiple of vector length (arg 1)203 parsing failures.
row # A tibble: 5 x 5 col     row col   expected               actual file                                                                                                                         expected   <int> <chr> <chr>                  <chr>  <chr>                                                                                                                        actual 1  1941 PHENO no trailing characters ;0     'data/maf/995c0111-d90b-4140-bee7-3845436c3b42/TCGA.BRCA.mutect.995c0111-d90b-4140-bee7-3845436c3b42.DR-10.0.somatic.maf.gz' file 2  3843 PHENO no trailing characters ;0     'data/maf/995c0111-d90b-4140-bee7-3845436c3b42/TCGA.BRCA.mutect.995c0111-d90b-4140-bee7-3845436c3b42.DR-10.0.somatic.maf.gz' row 3  4468 PHENO no trailing characters ;0     'data/maf/995c0111-d90b-4140-bee7-3845436c3b42/TCGA.BRCA.mutect.995c0111-d90b-4140-bee7-3845436c3b42.DR-10.0.somatic.maf.gz' col 4  6145 PHENO no trailing characters ;0     'data/maf/995c0111-d90b-4140-bee7-3845436c3b42/TCGA.BRCA.mutect.995c0111-d90b-4140-bee7-3845436c3b42.DR-10.0.somatic.maf.gz' expected 5  9783 PHENO no trailing characters ;1     'data/maf/995c0111-d90b-4140-bee7-3845436c3b42/TCGA.BRCA.mutect.995c0111-d90b-4140-bee7-3845436c3b42.DR-10.0.somatic.maf.gz'
... ................................. ... ........................................................................................................................................................................ ........ ..................................................................................................................................................................................................................................................................................................... ...... ................................................................................................................................................................................................. .... ................................................................................................................................................................................................. ... ................................................................................................................................................................................................. ... ................................................................................................................................................................................................. ........ .................................................................................................................................................................................................
See problems(...) for more details.

Preview data

print(dim(df))

[1] 120988    120

Warning messages:
1: Unknown or uninitialised column: 'GENE'. 
2: Unknown or uninitialised column: 'GENE'. 
3: Unknown or uninitialised column: 'GENE'. 
4: Unknown or uninitialised column: 'GENE'. 
5: Unknown or uninitialised column: 'GENE'. 

head(df, 10)

Read & concatenate multiple files

## Define column types
col_types = cols_only(
  Chromosome = 'c',
  Start_Position = 'i',
  End_Position = 'i',
  SYMBOL = 'c',
  Reference_Allele = 'c',
  Allele = 'c', 
  Variant_Classification = 'c', 
  IMPACT = 'c',
  Variant_Type = 'c',
  Tumor_Sample_Barcode = 'c'
)

Warning message:
Unknown or uninitialised column: 'GENE'. 

## Concatenate vertically
in_paths = c(
  in_path_varscan,
  in_path_muse,
  in_path_ss,
  in_path_mutect
)
df = bind_rows(lapply(
  in_paths, 
  read_tsv, 
  col_types = col_types,
  comment = '#'
))

|===============                                                                   |  18%   24 MB
|===============                                                                   |  18%   24 MB
|===============                                                                   |  19%   24 MB
|===============                                                                   |  19%   24 MB
|===============                                                                   |  19%   24 MB
|================                                                                  |  19%   25 MB
|================                                                                  |  19%   25 MB
|================                                                                  |  19%   25 MB
|================                                                                  |  19%   25 MB
|================                                                                  |  19%   25 MB
|================                                                                  |  19%   25 MB
|================                                                                  |  19%   25 MB
|================                                                                  |  19%   25 MB
|================                                                                  |  20%   25 MB
|================                                                                  |  20%   26 MB
|================                                                                  |  20%   26 MB
|================                                                                  |  20%   26 MB
|================                                                                  |  20%   26 MB
|=================                                                                 |  20%   26 MB
|=================                                                                 |  20%   26 MB
|=================                                                                 |  20%   26 MB
|=================                                                                 |  20%   26 MB
|=================                                                                 |  20%   27 MB
|=================                                                                 |  20%   27 MB
|=================                                                                 |  21%   27 MB
|=================                                                                 |  21%   27 MB
|=================                                                                 |  21%   27 MB
|=================                                                                 |  21%   27 MB
|=================                                                                 |  21%   27 MB
|=================                                                                 |  21%   27 MB
|=================                                                                 |  21%   27 MB
|=================                                                                 |  21%   28 MB
|==================                                                                |  21%   28 MB
|==================                                                                |  21%   28 MB
|==================                                                                |  21%   28 MB
|==================                                                                |  22%   28 MB
|==================                                                                |  22%   28 MB
|==================                                                                |  22%   28 MB
|==================                                                                |  22%   28 MB
|==================                                                                |  22%   28 MB
|==================                                                                |  22%   29 MB
|==================                                                                |  22%   29 MB
|==================                                                                |  22%   29 MB
|==================                                                                |  22%   29 MB
|==================                                                                |  22%   29 MB
|===================                                                               |  22%   29 MB
|===================                                                               |  22%   29 MB
|===================                                                               |  23%   29 MB
|===================                                                               |  23%   30 MB
|===================                                                               |  23%   30 MB
|===================                                                               |  23%   30 MB
|===================                                                               |  23%   30 MB
|===================                                                               |  23%   30 MB
|===================                                                               |  23%   30 MB
|===================                                                               |  23%   30 MB
|===================                                                               |  23%   30 MB
|===================                                                               |  23%   30 MB
|===================                                                               |  23%   31 MB
|===================                                                               |  24%   31 MB
|====================                                                              |  24%   31 MB
|====================                                                              |  24%   31 MB
|====================                                                              |  24%   31 MB
|====================                                                              |  24%   31 MB
|====================                                                              |  24%   31 MB
|====================                                                              |  24%   31 MB
|====================                                                              |  24%   32 MB
|====================                                                              |  24%   32 MB
|====================                                                              |  24%   32 MB
|====================                                                              |  24%   32 MB
|====================                                                              |  25%   32 MB
|====================                                                              |  25%   32 MB
|====================                                                              |  25%   32 MB
|=====================                                                             |  25%   32 MB
|=====================                                                             |  25%   32 MB
|=====================                                                             |  25%   33 MB
|=====================                                                             |  25%   33 MB
|=====================                                                             |  25%   33 MB
|=====================                                                             |  25%   33 MB
|=====================                                                             |  25%   33 MB
|=====================                                                             |  25%   33 MB
|=====================                                                             |  26%   33 MB
|=====================                                                             |  26%   33 MB
|=====================                                                             |  26%   33 MB
|=====================                                                             |  26%   34 MB
|=====================                                                             |  26%   34 MB
|=====================                                                             |  26%   34 MB
|======================                                                            |  26%   34 MB
|======================                                                            |  26%   34 MB
|======================                                                            |  26%   34 MB
|======================                                                            |  26%   34 MB
|======================                                                            |  26%   34 MB
|======================                                                            |  27%   35 MB
|======================                                                            |  27%   35 MB
|======================                                                            |  27%   35 MB
|======================                                                            |  27%   35 MB
|======================                                                            |  27%   35 MB
|======================                                                            |  27%   35 MB
|======================                                                            |  27%   35 MB
|======================                                                            |  27%   35 MB
|=======================                                                           |  27%   35 MB
|=======================                                                           |  27%   36 MB
|=======================                                                           |  27%   36 MB
|=======================                                                           |  27%   36 MB
|=======================                                                           |  28%   36 MB
|=======================                                                           |  28%   36 MB
|=======================                                                           |  28%   36 MB
|=======================                                                           |  28%   36 MB
|=======================                                                           |  28%   36 MB
|=======================                                                           |  28%   36 MB
|=======================                                                           |  28%   37 MB
|=======================                                                           |  28%   37 MB
|=======================                                                           |  28%   37 MB
|=======================                                                           |  28%   37 MB
|========================                                                          |  28%   37 MB
|========================                                                          |  29%   37 MB
|========================                                                          |  29%   37 MB
|========================                                                          |  29%   37 MB
|========================                                                          |  29%   38 MB
|========================                                                          |  29%   38 MB
|========================                                                          |  29%   38 MB
|========================                                                          |  29%   38 MB
|========================                                                          |  29%   38 MB
|========================                                                          |  29%   38 MB
|========================                                                          |  29%   38 MB
|========================                                                          |  29%   38 MB
|========================                                                          |  30%   38 MB
|=========================                                                         |  30%   39 MB
|=========================                                                         |  30%   39 MB
|=========================                                                         |  30%   39 MB
|=========================                                                         |  30%   39 MB
|=========================                                                         |  30%   39 MB
|=========================                                                         |  30%   39 MB
|=========================                                                         |  30%   39 MB
|=========================                                                         |  30%   39 MB
|=========================                                                         |  30%   39 MB
|=========================                                                         |  30%   40 MB
|=========================                                                         |  31%   40 MB
|=========================                                                         |  31%   40 MB
|=========================                                                         |  31%   40 MB
|=========================                                                         |  31%   40 MB
|==========================                                                        |  31%   40 MB
|==========================                                                        |  31%   40 MB
|==========================                                                        |  31%   40 MB
|==========================                                                        |  31%   40 MB
|==========================                                                        |  31%   41 MB
|==========================                                                        |  31%   41 MB
|==========================                                                        |  31%   41 MB
|==========================                                                        |  31%   41 MB
|==========================                                                        |  32%   41 MB
|==========================                                                        |  32%   41 MB
|==========================                                                        |  32%   41 MB
|==========================                                                        |  32%   41 MB
|==========================                                                        |  32%   42 MB
|==========================                                                        |  32%   42 MB
|===========================                                                       |  32%   42 MB
|===========================                                                       |  32%   42 MB
|===========================                                                       |  32%   42 MB
|===========================                                                       |  32%   42 MB
|===========================                                                       |  32%   42 MB
|===========================                                                       |  33%   42 MB
|===========================                                                       |  33%   42 MB
|===========================                                                       |  33%   43 MB
|===========================                                                       |  33%   43 MB
|===========================                                                       |  33%   43 MB
|===========================                                                       |  33%   43 MB
|===========================                                                       |  33%   43 MB
|===========================                                                       |  33%   43 MB
|============================                                                      |  33%   43 MB
|============================                                                      |  33%   43 MB
|============================                                                      |  33%   43 MB
|============================                                                      |  34%   44 MB
|============================                                                      |  34%   44 MB
|============================                                                      |  34%   44 MB
|============================                                                      |  34%   44 MB
|============================                                                      |  34%   44 MB
|============================                                                      |  34%   44 MB
|============================                                                      |  34%   44 MB
|============================                                                      |  34%   44 MB
|============================                                                      |  34%   45 MB
|============================                                                      |  34%   45 MB
|============================                                                      |  34%   45 MB
|=============================                                                     |  35%   45 MB
|=============================                                                     |  35%   45 MB
|=============================                                                     |  35%   45 MB
|=============================                                                     |  35%   45 MB
|=============================                                                     |  35%   45 MB
|=============================                                                     |  35%   45 MB
|=============================                                                     |  35%   46 MB
|=============================                                                     |  35%   46 MB
|=============================                                                     |  35%   46 MB
|=============================                                                     |  35%   46 MB
|=============================                                                     |  35%   46 MB
|=============================                                                     |  35%   46 MB
|=============================                                                     |  36%   46 MB
|==============================                                                    |  36%   46 MB
|==============================                                                    |  36%   47 MB
|==============================                                                    |  36%   47 MB
|==============================                                                    |  36%   47 MB
|==============================                                                    |  36%   47 MB
|==============================                                                    |  36%   47 MB
|==============================                                                    |  36%   47 MB
|==============================                                                    |  36%   47 MB
|==============================                                                    |  36%   47 MB
|==============================                                                    |  36%   47 MB
|==============================                                                    |  37%   48 MB
|==============================                                                    |  37%   48 MB
|==============================                                                    |  37%   48 MB
|==============================                                                    |  37%   48 MB
|===============================                                                   |  37%   48 MB
|===============================                                                   |  37%   48 MB
|===============================                                                   |  37%   48 MB
|===============================                                                   |  37%   48 MB
|===============================                                                   |  37%   48 MB
|===============================                                                   |  37%   49 MB
|===============================                                                   |  37%   49 MB
|===============================                                                   |  37%   49 MB
|===============================                                                   |  38%   49 MB
|===============================                                                   |  38%   49 MB
|===============================                                                   |  38%   49 MB
|===============================                                                   |  38%   49 MB
|===============================                                                   |  38%   49 MB
|===============================                                                   |  38%   49 MB
|================================                                                  |  38%   50 MB
|================================                                                  |  38%   50 MB
|================================                                                  |  38%   50 MB
|================================                                                  |  38%   50 MB
|================================                                                  |  38%   50 MB
|================================                                                  |  39%   50 MB
|================================                                                  |  39%   50 MB
|================================                                                  |  39%   50 MB
|================================                                                  |  39%   50 MB
|================================                                                  |  39%   51 MB
|================================                                                  |  39%   51 MB
|================================                                                  |  39%   51 MB
|================================                                                  |  39%   51 MB
|================================                                                  |  39%   51 MB
|=================================                                                 |  39%   51 MB
|=================================                                                 |  39%   51 MB
|=================================                                                 |  39%   51 MB
|=================================                                                 |  40%   51 MB
|=================================                                                 |  40%   52 MB
|=================================                                                 |  40%   52 MB
|=================================                                                 |  40%   52 MB
|=================================                                                 |  40%   52 MB
|=================================                                                 |  40%   52 MB
|=================================                                                 |  40%   52 MB
|=================================                                                 |  40%   52 MB
|=================================                                                 |  40%   52 MB
|=================================                                                 |  40%   53 MB
|==================================                                                |  40%   53 MB
|==================================                                                |  41%   53 MB
|==================================                                                |  41%   53 MB
|==================================                                                |  41%   53 MB
|==================================                                                |  41%   53 MB
|==================================                                                |  41%   53 MB
|==================================                                                |  41%   53 MB
|==================================                                                |  41%   53 MB
|==================================                                                |  41%   54 MB
|==================================                                                |  41%   54 MB
|==================================                                                |  41%   54 MB
|==================================                                                |  41%   54 MB
|==================================                                                |  42%   54 MB
|==================================                                                |  42%   54 MB
|===================================                                               |  42%   54 MB
|===================================                                               |  42%   54 MB
|===================================                                               |  42%   54 MB
|===================================                                               |  42%   55 MB
|===================================                                               |  42%   55 MB
|===================================                                               |  42%   55 MB
|===================================                                               |  42%   55 MB
|===================================                                               |  42%   55 MB
|===================================                                               |  42%   55 MB
|===================================                                               |  43%   55 MB
|===================================                                               |  43%   55 MB
|===================================                                               |  43%   56 MB
|===================================                                               |  43%   56 MB
|====================================                                              |  43%   56 MB
|====================================                                              |  43%   56 MB
|====================================                                              |  43%   56 MB
|====================================                                              |  43%   56 MB
|====================================                                              |  43%   56 MB
|====================================                                              |  43%   56 MB
|====================================                                              |  43%   56 MB
|====================================                                              |  44%   57 MB
|====================================                                              |  44%   57 MB
|====================================                                              |  44%   57 MB
|====================================                                              |  44%   57 MB
|====================================                                              |  44%   57 MB
|====================================                                              |  44%   57 MB
|====================================                                              |  44%   57 MB
|=====================================                                             |  44%   57 MB
|=====================================                                             |  44%   58 MB
|=====================================                                             |  44%   58 MB
|=====================================                                             |  44%   58 MB
|=====================================                                             |  45%   58 MB
|=====================================                                             |  45%   58 MB
|=====================================                                             |  45%   58 MB
|=====================================                                             |  45%   58 MB
|=====================================                                             |  45%   58 MB
|=====================================                                             |  45%   58 MB
|=====================================                                             |  45%   59 MB
|=====================================                                             |  45%   59 MB
|=====================================                                             |  45%   59 MB
|======================================                                            |  45%   59 MB
|======================================                                            |  45%   59 MB
|======================================                                            |  46%   59 MB
|======================================                                            |  46%   59 MB
|======================================                                            |  46%   59 MB
|======================================                                            |  46%   59 MB
|======================================                                            |  46%   60 MB
|======================================                                            |  46%   60 MB
|======================================                                            |  46%   60 MB
|======================================                                            |  46%   60 MB
|======================================                                            |  46%   60 MB
|======================================                                            |  46%   60 MB
|======================================                                            |  46%   60 MB
|=======================================                                           |  47%   60 MB
|=======================================                                           |  47%   61 MB
|=======================================                                           |  47%   61 MB
|=======================================                                           |  47%   61 MB
|=======================================                                           |  47%   61 MB
|=======================================                                           |  47%   61 MB
|=======================================                                           |  47%   61 MB
|=======================================                                           |  47%   61 MB
|=======================================                                           |  47%   61 MB
|=======================================                                           |  47%   61 MB
|=======================================                                           |  47%   62 MB
|=======================================                                           |  48%   62 MB
|=======================================                                           |  48%   62 MB
|=======================================                                           |  48%   62 MB
|========================================                                          |  48%   62 MB
|========================================                                          |  48%   62 MB
|========================================                                          |  48%   62 MB
|========================================                                          |  48%   62 MB
|========================================                                          |  48%   63 MB
|========================================                                          |  48%   63 MB
|========================================                                          |  48%   63 MB
|========================================                                          |  48%   63 MB
|========================================                                          |  48%   63 MB
|========================================                                          |  49%   63 MB
|========================================                                          |  49%   63 MB
|========================================                                          |  49%   63 MB
|========================================                                          |  49%   63 MB
|=========================================                                         |  49%   64 MB
|=========================================                                         |  49%   64 MB
|=========================================                                         |  49%   64 MB
|=========================================                                         |  49%   64 MB
|=========================================                                         |  49%   64 MB
|=========================================                                         |  49%   64 MB
|=========================================                                         |  49%   64 MB
|=========================================                                         |  50%   64 MB
|=========================================                                         |  50%   64 MB
|=========================================                                         |  50%   65 MB
|=========================================                                         |  50%   65 MB
|=========================================                                         |  50%   65 MB
|=========================================                                         |  50%   65 MB
|=========================================                                         |  50%   65 MB
|==========================================                                        |  50%   65 MB
|==========================================                                        |  50%   65 MB
|==========================================                                        |  50%   65 MB
|==========================================                                        |  50%   66 MB
|==========================================                                        |  51%   66 MB
|==========================================                                        |  51%   66 MB
|==========================================                                        |  51%   66 MB
|==========================================                                        |  51%   66 MB
|==========================================                                        |  51%   66 MB
|==========================================                                        |  51%   66 MB
|==========================================                                        |  51%   66 MB
|==========================================                                        |  51%   66 MB
|==========================================                                        |  51%   67 MB
|===========================================                                       |  51%   67 MB
|===========================================                                       |  51%   67 MB
|===========================================                                       |  52%   67 MB
|===========================================                                       |  52%   67 MB
|===========================================                                       |  52%   67 MB
|===========================================                                       |  52%   67 MB
|===========================================                                       |  52%   67 MB
|===========================================                                       |  52%   67 MB
|===========================================                                       |  52%   68 MB
|===========================================                                       |  52%   68 MB
|===========================================                                       |  52%   68 MB
|===========================================                                       |  52%   68 MB
|===========================================                                       |  52%   68 MB
|===========================================                                       |  52%   68 MB
|============================================                                      |  53%   68 MB
|============================================                                      |  53%   68 MB
|============================================                                      |  53%   69 MB
|============================================                                      |  53%   69 MB
|============================================                                      |  53%   69 MB
|============================================                                      |  53%   69 MB
|============================================                                      |  53%   69 MB
|============================================                                      |  53%   69 MB
|============================================                                      |  53%   69 MB
|============================================                                      |  53%   69 MB
|============================================                                      |  53%   69 MB
|============================================                                      |  54%   70 MB
|============================================                                      |  54%   70 MB
|=============================================                                     |  54%   70 MB
|=============================================                                     |  54%   70 MB
|=============================================                                     |  54%   70 MB
|=============================================                                     |  54%   70 MB
|=============================================                                     |  54%   70 MB
|=============================================                                     |  54%   70 MB
|=============================================                                     |  54%   71 MB
|=============================================                                     |  54%   71 MB
|=============================================                                     |  54%   71 MB
|=============================================                                     |  55%   71 MB
|=============================================                                     |  55%   71 MB
|=============================================                                     |  55%   71 MB
|=============================================                                     |  55%   71 MB
|==============================================                                    |  55%   71 MB
|==============================================                                    |  55%   71 MB
|==============================================                                    |  55%   72 MB
|==============================================                                    |  55%   72 MB
|==============================================                                    |  55%   72 MB
|==============================================                                    |  55%   72 MB
|==============================================                                    |  55%   72 MB
|==============================================                                    |  56%   72 MB
|==============================================                                    |  56%   72 MB
|==============================================                                    |  56%   72 MB
|==============================================                                    |  56%   72 MB
|==============================================                                    |  56%   73 MB
|==============================================                                    |  56%   73 MB
|==============================================                                    |  56%   73 MB
|===============================================                                   |  56%   73 MB
|===============================================                                   |  56%   73 MB
|===============================================                                   |  56%   73 MB
|===============================================                                   |  56%   73 MB
|===============================================                                   |  56%   73 MB
|===============================================                                   |  57%   74 MB
|===============================================                                   |  57%   74 MB
|===============================================                                   |  57%   74 MB
|===============================================                                   |  57%   74 MB
|===============================================                                   |  57%   74 MB
|===============================================                                   |  57%   74 MB
|===============================================                                   |  57%   74 MB
|===============================================                                   |  57%   74 MB
|===============================================                                   |  57%   74 MB
|================================================                                  |  57%   75 MB
|================================================                                  |  57%   75 MB
|================================================                                  |  58%   75 MB
|================================================                                  |  58%   75 MB
|================================================                                  |  58%   75 MB
|================================================                                  |  58%   75 MB
|================================================                                  |  58%   75 MB
|================================================                                  |  58%   75 MB
|================================================                                  |  58%   75 MB
|================================================                                  |  58%   76 MB
|================================================                                  |  58%   76 MB
|================================================                                  |  58%   76 MB
|================================================                                  |  58%   76 MB
|================================================                                  |  59%   76 MB
|=================================================                                 |  59%   76 MB
|=================================================                                 |  59%   76 MB
|=================================================                                 |  59%   76 MB
|=================================================                                 |  59%   76 MB
|=================================================                                 |  59%   77 MB
|=================================================                                 |  59%   77 MB
|=================================================                                 |  59%   77 MB
|=================================================                                 |  59%   77 MB
|=================================================                                 |  59%   77 MB
|=================================================                                 |  59%   77 MB
|=================================================                                 |  59%   77 MB
|=================================================                                 |  60%   77 MB
|=================================================                                 |  60%   77 MB
|=================================================                                 |  60%   78 MB
|==================================================                                |  60%   78 MB
|==================================================                                |  60%   78 MB
|==================================================                                |  60%   78 MB
|==================================================                                |  60%   78 MB
|==================================================                                |  60%   78 MB
|==================================================                                |  60%   78 MB
|==================================================                                |  60%   78 MB
|==================================================                                |  60%   79 MB
|==================================================                                |  61%   79 MB
|==================================================                                |  61%   79 MB
|==================================================                                |  61%   79 MB
|==================================================                                |  61%   79 MB
|===================================================                               |  61%   79 MB
|===================================================                               |  61%   79 MB
|===================================================                               |  61%   79 MB
|===================================================                               |  61%   80 MB
|===================================================                               |  61%   80 MB
|===================================================                               |  61%   80 MB
|===================================================                               |  62%   80 MB
|===================================================                               |  62%   80 MB
|===================================================                               |  62%   80 MB
|===================================================                               |  62%   80 MB
|===================================================                               |  62%   80 MB
|===================================================                               |  62%   81 MB
|===================================================                               |  62%   81 MB
|====================================================                              |  62%   81 MB
|====================================================                              |  62%   81 MB
|====================================================                              |  62%   81 MB
|====================================================                              |  62%   81 MB
|====================================================                              |  62%   81 MB
|====================================================                              |  63%   81 MB
|====================================================                              |  63%   81 MB
|====================================================                              |  63%   82 MB
|====================================================                              |  63%   82 MB
|====================================================                              |  63%   82 MB
|====================================================                              |  63%   82 MB
|====================================================                              |  63%   82 MB
|====================================================                              |  63%   82 MB
|====================================================                              |  63%   82 MB
|=====================================================                             |  63%   82 MB
|=====================================================                             |  63%   82 MB
|=====================================================                             |  64%   83 MB
|=====================================================                             |  64%   83 MB
|=====================================================                             |  64%   83 MB
|=====================================================                             |  64%   83 MB
|=====================================================                             |  64%   83 MB
|=====================================================                             |  64%   83 MB
|=====================================================                             |  64%   83 MB
|=====================================================                             |  64%   83 MB
|=====================================================                             |  64%   83 MB
|=====================================================                             |  64%   84 MB
|=====================================================                             |  64%   84 MB
|=====================================================                             |  65%   84 MB
|======================================================                            |  65%   84 MB
|======================================================                            |  65%   84 MB
|======================================================                            |  65%   84 MB
|======================================================                            |  65%   84 MB
|======================================================                            |  65%   84 MB
|======================================================                            |  65%   85 MB
|======================================================                            |  65%   85 MB
|======================================================                            |  65%   85 MB
|======================================================                            |  65%   85 MB
|======================================================                            |  65%   85 MB
|======================================================                            |  66%   85 MB
|======================================================                            |  66%   85 MB
|======================================================                            |  66%   85 MB
|=======================================================                           |  66%   85 MB
|=======================================================                           |  66%   86 MB
|=======================================================                           |  66%   86 MB
|=======================================================                           |  66%   86 MB
|=======================================================                           |  66%   86 MB
|=======================================================                           |  66%   86 MB
|=======================================================                           |  66%   86 MB
|=======================================================                           |  66%   86 MB
|=======================================================                           |  67%   86 MB
|=======================================================                           |  67%   87 MB
|=======================================================                           |  67%   87 MB
|=======================================================                           |  67%   87 MB
|=======================================================                           |  67%   87 MB
|========================================================                          |  67%   87 MB
|========================================================                          |  67%   87 MB
|========================================================                          |  67%   87 MB
|========================================================                          |  67%   87 MB
|========================================================                          |  67%   87 MB
|========================================================                          |  67%   88 MB
|========================================================                          |  68%   88 MB
|========================================================                          |  68%   88 MB
|========================================================                          |  68%   88 MB
|========================================================                          |  68%   88 MB
|========================================================                          |  68%   88 MB
|========================================================                          |  68%   88 MB
|========================================================                          |  68%   88 MB
|========================================================                          |  68%   88 MB
|=========================================================                         |  68%   89 MB
|=========================================================                         |  68%   89 MB
|=========================================================                         |  68%   89 MB
|=========================================================                         |  68%   89 MB
|=========================================================                         |  69%   89 MB
|=========================================================                         |  69%   89 MB
|=========================================================                         |  69%   89 MB
|=========================================================                         |  69%   89 MB
|=========================================================                         |  69%   90 MB
|=========================================================                         |  69%   90 MB
|=========================================================                         |  69%   90 MB
|=========================================================                         |  69%   90 MB
|=========================================================                         |  69%   90 MB
|==========================================================                        |  69%   90 MB
|==========================================================                        |  70%   90 MB
|==========================================================                        |  70%   90 MB
|==========================================================                        |  70%   90 MB
|==========================================================                        |  70%   91 MB
|==========================================================                        |  70%   91 MB
|==========================================================                        |  70%   91 MB
|==========================================================                        |  70%   91 MB
|==========================================================                        |  70%   91 MB
|==========================================================                        |  70%   91 MB
|==========================================================                        |  70%   91 MB
|==========================================================                        |  70%   91 MB
|==========================================================                        |  70%   91 MB
|==========================================================                        |  71%   92 MB
|===========================================================                       |  71%   92 MB
|===========================================================                       |  71%   92 MB
|===========================================================                       |  71%   92 MB
|===========================================================                       |  71%   92 MB
|===========================================================                       |  71%   92 MB
|===========================================================                       |  71%   92 MB
|===========================================================                       |  71%   92 MB
|===========================================================                       |  71%   93 MB
|===========================================================                       |  71%   93 MB
|===========================================================                       |  71%   93 MB
|===========================================================                       |  72%   93 MB
|===========================================================                       |  72%   93 MB
|===========================================================                       |  72%   93 MB
|===========================================================                       |  72%   93 MB
|============================================================                      |  72%   93 MB
|============================================================                      |  72%   93 MB
|============================================================                      |  72%   94 MB
|============================================================                      |  72%   94 MB
|============================================================                      |  72%   94 MB
|============================================================                      |  72%   94 MB
|============================================================                      |  72%   94 MB
|============================================================                      |  73%   94 MB
|============================================================                      |  73%   94 MB
|============================================================                      |  73%   94 MB
|============================================================                      |  73%   94 MB
|============================================================                      |  73%   95 MB
|============================================================                      |  73%   95 MB
|=============================================================                     |  73%   95 MB
|=============================================================                     |  73%   95 MB
|=============================================================                     |  73%   95 MB
|=============================================================                     |  73%   95 MB
|=============================================================                     |  73%   95 MB
|=============================================================                     |  73%   95 MB
|=============================================================                     |  74%   96 MB
|=============================================================                     |  74%   96 MB
|=============================================================                     |  74%   96 MB
|=============================================================                     |  74%   96 MB
|=============================================================                     |  74%   96 MB
|=============================================================                     |  74%   96 MB
|=============================================================                     |  74%   96 MB
|==============================================================                    |  74%   96 MB
|==============================================================                    |  74%   96 MB
|==============================================================                    |  74%   97 MB
|==============================================================                    |  74%   97 MB
|==============================================================                    |  75%   97 MB
|==============================================================                    |  75%   97 MB
|==============================================================                    |  75%   97 MB
|==============================================================                    |  75%   97 MB
|==============================================================                    |  75%   97 MB
|==============================================================                    |  75%   97 MB
|==============================================================                    |  75%   98 MB
|==============================================================                    |  75%   98 MB
|==============================================================                    |  75%   98 MB
|==============================================================                    |  75%   98 MB
|===============================================================                   |  75%   98 MB
|===============================================================                   |  76%   98 MB
|===============================================================                   |  76%   98 MB
|===============================================================                   |  76%   98 MB
|===============================================================                   |  76%   98 MB
|===============================================================                   |  76%   99 MB
|===============================================================                   |  76%   99 MB
|===============================================================                   |  76%   99 MB
|===============================================================                   |  76%   99 MB
|===============================================================                   |  76%   99 MB
|===============================================================                   |  76%   99 MB
|===============================================================                   |  76%   99 MB
|===============================================================                   |  77%   99 MB
|================================================================                  |  77%   99 MB
|================================================================                  |  77%  100 MB
|================================================================                  |  77%  100 MB
|================================================================                  |  77%  100 MB
|================================================================                  |  77%  100 MB
|================================================================                  |  77%  100 MB
|================================================================                  |  77%  100 MB
|================================================================                  |  77%  100 MB
|================================================================                  |  77%  100 MB
|================================================================                  |  77%  101 MB
|================================================================                  |  78%  101 MB
|================================================================                  |  78%  101 MB
|================================================================                  |  78%  101 MB
|================================================================                  |  78%  101 MB
|=================================================================                 |  78%  101 MB
|=================================================================                 |  78%  101 MB
|=================================================================                 |  78%  101 MB
|=================================================================                 |  78%  101 MB
|=================================================================                 |  78%  102 MB
|=================================================================                 |  78%  102 MB
|=================================================================                 |  78%  102 MB
|=================================================================                 |  79%  102 MB
|=================================================================                 |  79%  102 MB
|=================================================================                 |  79%  102 MB
|=================================================================                 |  79%  102 MB
|=================================================================                 |  79%  102 MB
|=================================================================                 |  79%  103 MB
|==================================================================                |  79%  103 MB
|==================================================================                |  79%  103 MB
|==================================================================                |  79%  103 MB
|==================================================================                |  79%  103 MB
|==================================================================                |  79%  103 MB
|==================================================================                |  79%  103 MB
|==================================================================                |  80%  103 MB
|==================================================================                |  80%  103 MB
|==================================================================                |  80%  104 MB
|==================================================================                |  80%  104 MB
|==================================================================                |  80%  104 MB
|==================================================================                |  80%  104 MB
|==================================================================                |  80%  104 MB
|==================================================================                |  80%  104 MB
|===================================================================               |  80%  104 MB
|===================================================================               |  80%  104 MB
|===================================================================               |  80%  104 MB
|===================================================================               |  81%  105 MB
|===================================================================               |  81%  105 MB
|===================================================================               |  81%  105 MB
|===================================================================               |  81%  105 MB
|===================================================================               |  81%  105 MB
|===================================================================               |  81%  105 MB
|===================================================================               |  81%  105 MB
|===================================================================               |  81%  105 MB
|===================================================================               |  81%  106 MB
|===================================================================               |  81%  106 MB
|====================================================================              |  81%  106 MB
|====================================================================              |  82%  106 MB
|====================================================================              |  82%  106 MB
|====================================================================              |  82%  106 MB
|====================================================================              |  82%  106 MB
|====================================================================              |  82%  106 MB
|====================================================================              |  82%  106 MB
|====================================================================              |  82%  107 MB
|====================================================================              |  82%  107 MB
|====================================================================              |  82%  107 MB
|====================================================================              |  82%  107 MB
|====================================================================              |  82%  107 MB
|====================================================================              |  83%  107 MB
|====================================================================              |  83%  107 MB
|=====================================================================             |  83%  107 MB
|=====================================================================             |  83%  107 MB
|=====================================================================             |  83%  108 MB
|=====================================================================             |  83%  108 MB
|=====================================================================             |  83%  108 MB
|=====================================================================             |  83%  108 MB
|=====================================================================             |  83%  108 MB
|=====================================================================             |  83%  108 MB
|=====================================================================             |  83%  108 MB
|=====================================================================             |  83%  108 MB
|=====================================================================             |  84%  108 MB
|=====================================================================             |  84%  109 MB
|=====================================================================             |  84%  109 MB
|======================================================================            |  84%  109 MB
|======================================================================            |  84%  109 MB
|======================================================================            |  84%  109 MB
|======================================================================            |  84%  109 MB
|======================================================================            |  84%  109 MB
|======================================================================            |  84%  109 MB
|======================================================================            |  84%  110 MB
|======================================================================            |  84%  110 MB
|======================================================================            |  85%  110 MB
|======================================================================            |  85%  110 MB
|======================================================================            |  85%  110 MB
|======================================================================            |  85%  110 MB
|======================================================================            |  85%  110 MB
|======================================================================            |  85%  110 MB
|=======================================================================           |  85%  111 MB
|=======================================================================           |  85%  111 MB
|=======================================================================           |  85%  111 MB
|=======================================================================           |  85%  111 MB
|=======================================================================           |  85%  111 MB
|=======================================================================           |  86%  111 MB
|=======================================================================           |  86%  111 MB
|=======================================================================           |  86%  111 MB
|=======================================================================           |  86%  111 MB
|=======================================================================           |  86%  111 MB
|=======================================================================           |  86%  112 MB
|=======================================================================           |  86%  112 MB
|=======================================================================           |  86%  112 MB
|========================================================================          |  86%  112 MB
|========================================================================          |  86%  112 MB
|========================================================================          |  86%  112 MB
|========================================================================          |  87%  112 MB
|========================================================================          |  87%  112 MB
|========================================================================          |  87%  113 MB
|========================================================================          |  87%  113 MB
|========================================================================          |  87%  113 MB
|========================================================================          |  87%  113 MB
|========================================================================          |  87%  113 MB
|========================================================================          |  87%  113 MB
|========================================================================          |  87%  113 MB
|========================================================================          |  87%  113 MB
|========================================================================          |  87%  113 MB
|=========================================================================         |  87%  114 MB
|=========================================================================         |  88%  114 MB
|=========================================================================         |  88%  114 MB
|=========================================================================         |  88%  114 MB
|=========================================================================         |  88%  114 MB
|=========================================================================         |  88%  114 MB
|=========================================================================         |  88%  114 MB
|=========================================================================         |  88%  114 MB
|=========================================================================         |  88%  115 MB
|=========================================================================         |  88%  115 MB
|=========================================================================         |  88%  115 MB
|=========================================================================         |  88%  115 MB
|=========================================================================         |  89%  115 MB
|=========================================================================         |  89%  115 MB
|==========================================================================        |  89%  115 MB
|==========================================================================        |  89%  115 MB
|==========================================================================        |  89%  115 MB
|==========================================================================        |  89%  116 MB
|==========================================================================        |  89%  116 MB
|==========================================================================        |  89%  116 MB
|==========================================================================        |  89%  116 MB
|==========================================================================        |  89%  116 MB
|==========================================================================        |  89%  116 MB
|==========================================================================        |  90%  116 MB
|==========================================================================        |  90%  116 MB
|==========================================================================        |  90%  116 MB
|==========================================================================        |  90%  117 MB
|===========================================================================       |  90%  117 MB
|===========================================================================       |  90%  117 MB
|===========================================================================       |  90%  117 MB
|===========================================================================       |  90%  117 MB
|===========================================================================       |  90%  117 MB
|===========================================================================       |  90%  117 MB
|===========================================================================       |  90%  117 MB
|===========================================================================       |  91%  117 MB
|===========================================================================       |  91%  118 MB
|===========================================================================       |  91%  118 MB
|===========================================================================       |  91%  118 MB
|===========================================================================       |  91%  118 MB
|===========================================================================       |  91%  118 MB
|===========================================================================       |  91%  118 MB
|============================================================================      |  91%  118 MB
|============================================================================      |  91%  118 MB
|============================================================================      |  91%  119 MB
|============================================================================      |  91%  119 MB
|============================================================================      |  92%  119 MB
|============================================================================      |  92%  119 MB
|============================================================================      |  92%  119 MB
|============================================================================      |  92%  119 MB
|============================================================================      |  92%  119 MB
|============================================================================      |  92%  119 MB
|============================================================================      |  92%  119 MB
|============================================================================      |  92%  120 MB
|============================================================================      |  92%  120 MB
|=============================================================================     |  92%  120 MB
|=============================================================================     |  92%  120 MB
|=============================================================================     |  93%  120 MB
|=============================================================================     |  93%  120 MB
|=============================================================================     |  93%  120 MB
|=============================================================================     |  93%  120 MB
|=============================================================================     |  93%  121 MB
|=============================================================================     |  93%  121 MB
|=============================================================================     |  93%  121 MB
|=============================================================================     |  93%  121 MB
|=============================================================================     |  93%  121 MB
|=============================================================================     |  93%  121 MB
|=============================================================================     |  93%  121 MB
|==============================================================================    |  93%  121 MB
|==============================================================================    |  94%  121 MB
|==============================================================================    |  94%  122 MB
|==============================================================================    |  94%  122 MB
|==============================================================================    |  94%  122 MB
|==============================================================================    |  94%  122 MB
|==============================================================================    |  94%  122 MB
|==============================================================================    |  94%  122 MB
|==============================================================================    |  94%  122 MB
|==============================================================================    |  94%  122 MB
|==============================================================================    |  94%  122 MB
|==============================================================================    |  94%  123 MB
|==============================================================================    |  95%  123 MB
|==============================================================================    |  95%  123 MB
|===============================================================================   |  95%  123 MB
|===============================================================================   |  95%  123 MB
|===============================================================================   |  95%  123 MB
|===============================================================================   |  95%  123 MB
|===============================================================================   |  95%  123 MB
|===============================================================================   |  95%  124 MB
|===============================================================================   |  95%  124 MB
|===============================================================================   |  95%  124 MB
|===============================================================================   |  95%  124 MB
|===============================================================================   |  96%  124 MB
|===============================================================================   |  96%  124 MB
|===============================================================================   |  96%  124 MB
|===============================================================================   |  96%  124 MB
|===============================================================================   |  96%  124 MB
|================================================================================  |  96%  125 MB
|================================================================================  |  96%  125 MB
|================================================================================  |  96%  125 MB
|================================================================================  |  96%  125 MB
|================================================================================  |  96%  125 MB
|================================================================================  |  96%  125 MB
|================================================================================  |  97%  125 MB
|================================================================================  |  97%  125 MB
|================================================================================  |  97%  125 MB
|================================================================================  |  97%  126 MB
|================================================================================  |  97%  126 MB
|================================================================================  |  97%  126 MB
|================================================================================  |  97%  126 MB
|================================================================================= |  97%  126 MB
|================================================================================= |  97%  126 MB
|================================================================================= |  97%  126 MB
|================================================================================= |  97%  126 MB
|================================================================================= |  97%  127 MB
|================================================================================= |  98%  127 MB
|================================================================================= |  98%  127 MB
|================================================================================= |  98%  127 MB
|================================================================================= |  98%  127 MB
|================================================================================= |  98%  127 MB
|================================================================================= |  98%  127 MB
|================================================================================= |  98%  127 MB
|================================================================================= |  98%  127 MB
|================================================================================= |  98%  128 MB
|==================================================================================|  98%  128 MB
|==================================================================================|  98%  128 MB
|==================================================================================|  99%  128 MB
|==================================================================================|  99%  128 MB
|==================================================================================|  99%  128 MB
|==================================================================================|  99%  128 MB
|==================================================================================|  99%  128 MB
|==================================================================================|  99%  129 MB
|==================================================================================|  99%  129 MB
|==================================================================================|  99%  129 MB
|==================================================================================|  99%  129 MB
|==================================================================================|  99%  129 MB
|==================================================================================|  99%  129 MB
|===================================================================================| 100%  129 MB

|===                                                                               |   4%    5 MB
|===                                                                               |   4%    5 MB
|===                                                                               |   4%    5 MB
|===                                                                               |   4%    5 MB
|===                                                                               |   4%    5 MB
|===                                                                               |   4%    5 MB
|===                                                                               |   4%    5 MB
|===                                                                               |   4%    6 MB
|====                                                                              |   4%    6 MB
|====                                                                              |   4%    6 MB
|====                                                                              |   5%    6 MB
|====                                                                              |   5%    6 MB
|====                                                                              |   5%    6 MB
|====                                                                              |   5%    6 MB
|====                                                                              |   5%    6 MB
|====                                                                              |   5%    6 MB
|====                                                                              |   5%    7 MB
|====                                                                              |   5%    7 MB
|====                                                                              |   5%    7 MB
|====                                                                              |   5%    7 MB
|====                                                                              |   5%    7 MB
|=====                                                                             |   6%    7 MB
|=====                                                                             |   6%    7 MB
|=====                                                                             |   6%    7 MB
|=====                                                                             |   6%    7 MB
|=====                                                                             |   6%    8 MB
|=====                                                                             |   6%    8 MB
|=====                                                                             |   6%    8 MB
|=====                                                                             |   6%    8 MB
|=====                                                                             |   6%    8 MB
|=====                                                                             |   6%    8 MB
|=====                                                                             |   6%    8 MB
|=====                                                                             |   7%    8 MB
|=====                                                                             |   7%    8 MB
|=====                                                                             |   7%    9 MB
|======                                                                            |   7%    9 MB
|======                                                                            |   7%    9 MB
|======                                                                            |   7%    9 MB
|======                                                                            |   7%    9 MB
|======                                                                            |   7%    9 MB
|======                                                                            |   7%    9 MB
|======                                                                            |   7%    9 MB
|======                                                                            |   7%    9 MB
|======                                                                            |   8%   10 MB
|======                                                                            |   8%   10 MB
|======                                                                            |   8%   10 MB
|======                                                                            |   8%   10 MB
|======                                                                            |   8%   10 MB
|=======                                                                           |   8%   10 MB
|=======                                                                           |   8%   10 MB
|=======                                                                           |   8%   10 MB
|=======                                                                           |   8%   10 MB
|=======                                                                           |   8%   11 MB
|=======                                                                           |   8%   11 MB
|=======                                                                           |   9%   11 MB
|=======                                                                           |   9%   11 MB
|=======                                                                           |   9%   11 MB
|=======                                                                           |   9%   11 MB
|=======                                                                           |   9%   11 MB
|=======                                                                           |   9%   11 MB
|=======                                                                           |   9%   12 MB
|========                                                                          |   9%   12 MB
|========                                                                          |   9%   12 MB
|========                                                                          |   9%   12 MB
|========                                                                          |   9%   12 MB
|========                                                                          |  10%   12 MB
|========                                                                          |  10%   12 MB
|========                                                                          |  10%   12 MB
|========                                                                          |  10%   12 MB
|========                                                                          |  10%   13 MB
|========                                                                          |  10%   13 MB
|========                                                                          |  10%   13 MB
|========                                                                          |  10%   13 MB
|========                                                                          |  10%   13 MB
|=========                                                                         |  10%   13 MB
|=========                                                                         |  10%   13 MB
|=========                                                                         |  11%   13 MB
|=========                                                                         |  11%   13 MB
|=========                                                                         |  11%   14 MB
|=========                                                                         |  11%   14 MB
|=========                                                                         |  11%   14 MB
|=========                                                                         |  11%   14 MB
|=========                                                                         |  11%   14 MB
|=========                                                                         |  11%   14 MB
|=========                                                                         |  11%   14 MB
|=========                                                                         |  11%   14 MB
|=========                                                                         |  11%   15 MB
|=========                                                                         |  12%   15 MB
|==========                                                                        |  12%   15 MB
|==========                                                                        |  12%   15 MB
|==========                                                                        |  12%   15 MB
|==========                                                                        |  12%   15 MB
|==========                                                                        |  12%   15 MB
|==========                                                                        |  12%   15 MB
|==========                                                                        |  12%   15 MB
|==========                                                                        |  12%   16 MB
|==========                                                                        |  12%   16 MB
|==========                                                                        |  12%   16 MB
|==========                                                                        |  13%   16 MB
|==========                                                                        |  13%   16 MB
|==========                                                                        |  13%   16 MB
|===========                                                                       |  13%   16 MB
|===========                                                                       |  13%   16 MB
|===========                                                                       |  13%   16 MB
|===========                                                                       |  13%   17 MB
|===========                                                                       |  13%   17 MB
|===========                                                                       |  13%   17 MB
|===========                                                                       |  13%   17 MB
|===========                                                                       |  13%   17 MB
|===========                                                                       |  14%   17 MB
|===========                                                                       |  14%   17 MB
|===========                                                                       |  14%   17 MB
|===========                                                                       |  14%   17 MB
|===========                                                                       |  14%   18 MB
|============                                                                      |  14%   18 MB
|============                                                                      |  14%   18 MB
|============                                                                      |  14%   18 MB
|============                                                                      |  14%   18 MB
|============                                                                      |  14%   18 MB
|============                                                                      |  14%   18 MB
|============                                                                      |  15%   18 MB
|============                                                                      |  15%   18 MB
|============                                                                      |  15%   19 MB
|============                                                                      |  15%   19 MB
|============                                                                      |  15%   19 MB
|============                                                                      |  15%   19 MB
|============                                                                      |  15%   19 MB
|=============                                                                     |  15%   19 MB
|=============                                                                     |  15%   19 MB
|=============                                                                     |  15%   19 MB
|=============                                                                     |  15%   20 MB
|=============                                                                     |  16%   20 MB
|=============                                                                     |  16%   20 MB
|=============                                                                     |  16%   20 MB
|=============                                                                     |  16%   20 MB
|=============                                                                     |  16%   20 MB
|=============                                                                     |  16%   20 MB
|=============                                                                     |  16%   20 MB
|=============                                                                     |  16%   20 MB
|=============                                                                     |  16%   21 MB
|==============                                                                    |  16%   21 MB
|==============                                                                    |  16%   21 MB
|==============                                                                    |  17%   21 MB
|==============                                                                    |  17%   21 MB
|==============                                                                    |  17%   21 MB
|==============                                                                    |  17%   21 MB
|==============                                                                    |  17%   21 MB
|==============                                                                    |  17%   22 MB
|==============                                                                    |  17%   22 MB
|==============                                                                    |  17%   22 MB
|==============                                                                    |  17%   22 MB
|==============                                                                    |  17%   22 MB
|==============                                                                    |  17%   22 MB
|===============                                                                   |  18%   22 MB
|===============                                                                   |  18%   22 MB
|===============                                                                   |  18%   22 MB
|===============                                                                   |  18%   23 MB
|===============                                                                   |  18%   23 MB
|===============                                                                   |  18%   23 MB
|===============                                                                   |  18%   23 MB
|===============                                                                   |  18%   23 MB
|===============                                                                   |  18%   23 MB
|===============                                                                   |  18%   23 MB
|===============                                                                   |  19%   23 MB
|===============                                                                   |  19%   23 MB
|===============                                                                   |  19%   24 MB
|================                                                                  |  19%   24 MB
|================                                                                  |  19%   24 MB
|================                                                                  |  19%   24 MB
|================                                                                  |  19%   24 MB
|================                                                                  |  19%   24 MB
|================                                                                  |  19%   24 MB
|================                                                                  |  19%   24 MB
|================                                                                  |  19%   25 MB
|================                                                                  |  20%   25 MB
|================                                                                  |  20%   25 MB
|================                                                                  |  20%   25 MB
|================                                                                  |  20%   25 MB
|================                                                                  |  20%   25 MB
|=================                                                                 |  20%   25 MB
|=================                                                                 |  20%   25 MB
|=================                                                                 |  20%   25 MB
|=================                                                                 |  20%   26 MB
|=================                                                                 |  20%   26 MB
|=================                                                                 |  20%   26 MB
|=================                                                                 |  21%   26 MB
|=================                                                                 |  21%   26 MB
|=================                                                                 |  21%   26 MB
|=================                                                                 |  21%   26 MB
|=================                                                                 |  21%   26 MB
|=================                                                                 |  21%   26 MB
|=================                                                                 |  21%   27 MB
|==================                                                                |  21%   27 MB
|==================                                                                |  21%   27 MB
|==================                                                                |  21%   27 MB
|==================                                                                |  21%   27 MB
|==================                                                                |  22%   27 MB
|==================                                                                |  22%   27 MB
|==================                                                                |  22%   27 MB
|==================                                                                |  22%   28 MB
|==================                                                                |  22%   28 MB
|==================                                                                |  22%   28 MB
|==================                                                                |  22%   28 MB
|==================                                                                |  22%   28 MB
|==================                                                                |  22%   28 MB
|==================                                                                |  22%   28 MB
|===================                                                               |  22%   28 MB
|===================                                                               |  23%   28 MB
|===================                                                               |  23%   29 MB
|===================                                                               |  23%   29 MB
|===================                                                               |  23%   29 MB
|===================                                                               |  23%   29 MB
|===================                                                               |  23%   29 MB
|===================                                                               |  23%   29 MB
|===================                                                               |  23%   29 MB
|===================                                                               |  23%   29 MB
|===================                                                               |  23%   29 MB
|===================                                                               |  23%   30 MB
|===================                                                               |  24%   30 MB
|===================                                                               |  24%   30 MB
|====================                                                              |  24%   30 MB
|====================                                                              |  24%   30 MB
|====================                                                              |  24%   30 MB
|====================                                                              |  24%   30 MB
|====================                                                              |  24%   30 MB
|====================                                                              |  24%   30 MB
|====================                                                              |  24%   31 MB
|====================                                                              |  24%   31 MB
|====================                                                              |  24%   31 MB
|====================                                                              |  25%   31 MB
|====================                                                              |  25%   31 MB
|====================                                                              |  25%   31 MB
|====================                                                              |  25%   31 MB
|=====================                                                             |  25%   31 MB
|=====================                                                             |  25%   31 MB
|=====================                                                             |  25%   32 MB
|=====================                                                             |  25%   32 MB
|=====================                                                             |  25%   32 MB
|=====================                                                             |  25%   32 MB
|=====================                                                             |  25%   32 MB
|=====================                                                             |  26%   32 MB
|=====================                                                             |  26%   32 MB
|=====================                                                             |  26%   32 MB
|=====================                                                             |  26%   33 MB
|=====================                                                             |  26%   33 MB
|=====================                                                             |  26%   33 MB
|======================                                                            |  26%   33 MB
|======================                                                            |  26%   33 MB
|======================                                                            |  26%   33 MB
|======================                                                            |  26%   33 MB
|======================                                                            |  26%   33 MB
|======================                                                            |  26%   33 MB
|======================                                                            |  27%   33 MB
|======================                                                            |  27%   34 MB
|======================                                                            |  27%   34 MB
|======================                                                            |  27%   34 MB
|======================                                                            |  27%   34 MB
|======================                                                            |  27%   34 MB
|======================                                                            |  27%   34 MB
|======================                                                            |  27%   34 MB
|=======================                                                           |  27%   34 MB
|=======================                                                           |  27%   34 MB
|=======================                                                           |  27%   35 MB
|=======================                                                           |  28%   35 MB
|=======================                                                           |  28%   35 MB
|=======================                                                           |  28%   35 MB
|=======================                                                           |  28%   35 MB
|=======================                                                           |  28%   35 MB
|=======================                                                           |  28%   35 MB
|=======================                                                           |  28%   35 MB
|=======================                                                           |  28%   36 MB
|=======================                                                           |  28%   36 MB
|=======================                                                           |  28%   36 MB
|========================                                                          |  28%   36 MB
|========================                                                          |  29%   36 MB
|========================                                                          |  29%   36 MB
|========================                                                          |  29%   36 MB
|========================                                                          |  29%   36 MB
|========================                                                          |  29%   36 MB
|========================                                                          |  29%   37 MB
|========================                                                          |  29%   37 MB
|========================                                                          |  29%   37 MB
|========================                                                          |  29%   37 MB
|========================                                                          |  29%   37 MB
|========================                                                          |  29%   37 MB
|========================                                                          |  30%   37 MB
|=========================                                                         |  30%   37 MB
|=========================                                                         |  30%   37 MB
|=========================                                                         |  30%   38 MB
|=========================                                                         |  30%   38 MB
|=========================                                                         |  30%   38 MB
|=========================                                                         |  30%   38 MB
|=========================                                                         |  30%   38 MB
|=========================                                                         |  30%   38 MB
|=========================                                                         |  30%   38 MB
|=========================                                                         |  30%   38 MB
|=========================                                                         |  31%   38 MB
|=========================                                                         |  31%   39 MB
|=========================                                                         |  31%   39 MB
|=========================                                                         |  31%   39 MB
|==========================                                                        |  31%   39 MB
|==========================                                                        |  31%   39 MB
|==========================                                                        |  31%   39 MB
|==========================                                                        |  31%   39 MB
|==========================                                                        |  31%   39 MB
|==========================                                                        |  31%   40 MB
|==========================                                                        |  31%   40 MB
|==========================                                                        |  32%   40 MB
|==========================                                                        |  32%   40 MB
|==========================                                                        |  32%   40 MB
|==========================                                                        |  32%   40 MB
|==========================                                                        |  32%   40 MB
|===========================                                                       |  32%   40 MB
|===========================                                                       |  32%   40 MB
|===========================                                                       |  32%   41 MB
|===========================                                                       |  32%   41 MB
|===========================                                                       |  32%   41 MB
|===========================                                                       |  32%   41 MB
|===========================                                                       |  33%   41 MB
|===========================                                                       |  33%   41 MB
|===========================                                                       |  33%   41 MB
|===========================                                                       |  33%   41 MB
|===========================                                                       |  33%   42 MB
|===========================                                                       |  33%   42 MB
|===========================                                                       |  33%   42 MB
|============================                                                      |  33%   42 MB
|============================                                                      |  33%   42 MB
|============================                                                      |  33%   42 MB
|============================                                                      |  34%   42 MB
|============================                                                      |  34%   42 MB
|============================                                                      |  34%   42 MB
|============================                                                      |  34%   43 MB
|============================                                                      |  34%   43 MB
|============================                                                      |  34%   43 MB
|============================                                                      |  34%   43 MB
|============================                                                      |  34%   43 MB
|============================                                                      |  34%   43 MB
|============================                                                      |  34%   43 MB
|=============================                                                     |  34%   43 MB
|=============================                                                     |  35%   43 MB
|=============================                                                     |  35%   44 MB
|=============================                                                     |  35%   44 MB
|=============================                                                     |  35%   44 MB
|=============================                                                     |  35%   44 MB
|=============================                                                     |  35%   44 MB
|=============================                                                     |  35%   44 MB
|=============================                                                     |  35%   44 MB
|=============================                                                     |  35%   44 MB
|=============================                                                     |  35%   45 MB
|=============================                                                     |  35%   45 MB
|=============================                                                     |  36%   45 MB
|=============================                                                     |  36%   45 MB
|==============================                                                    |  36%   45 MB
|==============================                                                    |  36%   45 MB
|==============================                                                    |  36%   45 MB
|==============================                                                    |  36%   45 MB
|==============================                                                    |  36%   45 MB
|==============================                                                    |  36%   46 MB
|==============================                                                    |  36%   46 MB
|==============================                                                    |  36%   46 MB
|==============================                                                    |  36%   46 MB
|==============================                                                    |  37%   46 MB
|==============================                                                    |  37%   46 MB
|==============================                                                    |  37%   46 MB
|==============================                                                    |  37%   46 MB
|===============================                                                   |  37%   46 MB
|===============================                                                   |  37%   47 MB
|===============================                                                   |  37%   47 MB
|===============================                                                   |  37%   47 MB
|===============================                                                   |  37%   47 MB
|===============================                                                   |  37%   47 MB
|===============================                                                   |  37%   47 MB
|===============================                                                   |  38%   47 MB
|===============================                                                   |  38%   47 MB
|===============================                                                   |  38%   48 MB
|===============================                                                   |  38%   48 MB
|===============================                                                   |  38%   48 MB
|===============================                                                   |  38%   48 MB
|================================                                                  |  38%   48 MB
|================================                                                  |  38%   48 MB
|================================                                                  |  38%   48 MB
|================================                                                  |  38%   48 MB
|================================                                                  |  38%   48 MB
|================================                                                  |  39%   49 MB
|================================                                                  |  39%   49 MB
|================================                                                  |  39%   49 MB
|================================                                                  |  39%   49 MB
|================================                                                  |  39%   49 MB
|================================                                                  |  39%   49 MB
|================================                                                  |  39%   49 MB
|================================                                                  |  39%   49 MB
|=================================                                                 |  39%   49 MB
|=================================                                                 |  39%   50 MB
|=================================                                                 |  39%   50 MB
|=================================                                                 |  40%   50 MB
|=================================                                                 |  40%   50 MB
|=================================                                                 |  40%   50 MB
|=================================                                                 |  40%   50 MB
|=================================                                                 |  40%   50 MB
|=================================                                                 |  40%   50 MB
|=================================                                                 |  40%   51 MB
|=================================                                                 |  40%   51 MB
|=================================                                                 |  40%   51 MB
|=================================                                                 |  40%   51 MB
|==================================                                                |  40%   51 MB
|==================================                                                |  41%   51 MB
|==================================                                                |  41%   51 MB
|==================================                                                |  41%   51 MB
|==================================                                                |  41%   51 MB
|==================================                                                |  41%   52 MB
|==================================                                                |  41%   52 MB
|==================================                                                |  41%   52 MB
|==================================                                                |  41%   52 MB
|==================================                                                |  41%   52 MB
|==================================                                                |  41%   52 MB
|==================================                                                |  41%   52 MB
|==================================                                                |  42%   52 MB
|==================================                                                |  42%   52 MB
|===================================                                               |  42%   53 MB
|===================================                                               |  42%   53 MB
|===================================                                               |  42%   53 MB
|===================================                                               |  42%   53 MB
|===================================                                               |  42%   53 MB
|===================================                                               |  42%   53 MB
|===================================                                               |  42%   53 MB
|===================================                                               |  42%   53 MB
|===================================                                               |  42%   53 MB
|===================================                                               |  43%   54 MB
|===================================                                               |  43%   54 MB
|===================================                                               |  43%   54 MB
|===================================                                               |  43%   54 MB
|====================================                                              |  43%   54 MB
|====================================                                              |  43%   54 MB
|====================================                                              |  43%   54 MB
|====================================                                              |  43%   54 MB
|====================================                                              |  43%   55 MB
|====================================                                              |  43%   55 MB
|====================================                                              |  44%   55 MB
|====================================                                              |  44%   55 MB
|====================================                                              |  44%   55 MB
|====================================                                              |  44%   55 MB
|====================================                                              |  44%   55 MB
|====================================                                              |  44%   55 MB
|====================================                                              |  44%   55 MB
|=====================================                                             |  44%   56 MB
|=====================================                                             |  44%   56 MB
|=====================================                                             |  44%   56 MB
|=====================================                                             |  44%   56 MB
|=====================================                                             |  45%   56 MB
|=====================================                                             |  45%   56 MB
|=====================================                                             |  45%   56 MB
|=====================================                                             |  45%   56 MB
|=====================================                                             |  45%   56 MB
|=====================================                                             |  45%   57 MB
|=====================================                                             |  45%   57 MB
|=====================================                                             |  45%   57 MB
|=====================================                                             |  45%   57 MB
|======================================                                            |  45%   57 MB
|======================================                                            |  45%   57 MB
|======================================                                            |  46%   57 MB
|======================================                                            |  46%   57 MB
|======================================                                            |  46%   58 MB
|======================================                                            |  46%   58 MB
|======================================                                            |  46%   58 MB
|======================================                                            |  46%   58 MB
|======================================                                            |  46%   58 MB
|======================================                                            |  46%   58 MB
|======================================                                            |  46%   58 MB
|======================================                                            |  46%   58 MB
|======================================                                            |  46%   58 MB
|=======================================                                           |  47%   59 MB
|=======================================                                           |  47%   59 MB
|=======================================                                           |  47%   59 MB
|=======================================                                           |  47%   59 MB
|=======================================                                           |  47%   59 MB
|=======================================                                           |  47%   59 MB
|=======================================                                           |  47%   59 MB
|=======================================                                           |  47%   59 MB
|=======================================                                           |  47%   59 MB
|=======================================                                           |  47%   60 MB
|=======================================                                           |  47%   60 MB
|=======================================                                           |  48%   60 MB
|=======================================                                           |  48%   60 MB
|========================================                                          |  48%   60 MB
|========================================                                          |  48%   60 MB
|========================================                                          |  48%   60 MB
|========================================                                          |  48%   60 MB
|========================================                                          |  48%   60 MB
|========================================                                          |  48%   61 MB
|========================================                                          |  48%   61 MB
|========================================                                          |  48%   61 MB
|========================================                                          |  48%   61 MB
|========================================                                          |  49%   61 MB
|========================================                                          |  49%   61 MB
|========================================                                          |  49%   61 MB
|========================================                                          |  49%   61 MB
|=========================================                                         |  49%   62 MB
|=========================================                                         |  49%   62 MB
|=========================================                                         |  49%   62 MB
|=========================================                                         |  49%   62 MB
|=========================================                                         |  49%   62 MB
|=========================================                                         |  49%   62 MB
|=========================================                                         |  49%   62 MB
|=========================================                                         |  50%   62 MB
|=========================================                                         |  50%   62 MB
|=========================================                                         |  50%   63 MB
|=========================================                                         |  50%   63 MB
|=========================================                                         |  50%   63 MB
|=========================================                                         |  50%   63 MB
|=========================================                                         |  50%   63 MB
|==========================================                                        |  50%   63 MB
|==========================================                                        |  50%   63 MB
|==========================================                                        |  50%   63 MB
|==========================================                                        |  50%   63 MB
|==========================================                                        |  51%   64 MB
|==========================================                                        |  51%   64 MB
|==========================================                                        |  51%   64 MB
|==========================================                                        |  51%   64 MB
|==========================================                                        |  51%   64 MB
|==========================================                                        |  51%   64 MB
|==========================================                                        |  51%   64 MB
|==========================================                                        |  51%   64 MB
|==========================================                                        |  51%   65 MB
|===========================================                                       |  51%   65 MB
|===========================================                                       |  51%   65 MB
|===========================================                                       |  52%   65 MB
|===========================================                                       |  52%   65 MB
|===========================================                                       |  52%   65 MB
|===========================================                                       |  52%   65 MB
|===========================================                                       |  52%   65 MB
|===========================================                                       |  52%   65 MB
|===========================================                                       |  52%   66 MB
|===========================================                                       |  52%   66 MB
|===========================================                                       |  52%   66 MB
|===========================================                                       |  52%   66 MB
|===========================================                                       |  53%   66 MB
|============================================                                      |  53%   66 MB
|============================================                                      |  53%   66 MB
|============================================                                      |  53%   66 MB
|============================================                                      |  53%   67 MB
|============================================                                      |  53%   67 MB
|============================================                                      |  53%   67 MB
|============================================                                      |  53%   67 MB
|============================================                                      |  53%   67 MB
|============================================                                      |  53%   67 MB
|============================================                                      |  53%   67 MB
|============================================                                      |  54%   67 MB
|============================================                                      |  54%   67 MB
|============================================                                      |  54%   68 MB
|=============================================                                     |  54%   68 MB
|=============================================                                     |  54%   68 MB
|=============================================                                     |  54%   68 MB
|=============================================                                     |  54%   68 MB
|=============================================                                     |  54%   68 MB
|=============================================                                     |  54%   68 MB
|=============================================                                     |  54%   68 MB
|=============================================                                     |  54%   68 MB
|=============================================                                     |  55%   69 MB
|=============================================                                     |  55%   69 MB
|=============================================                                     |  55%   69 MB
|=============================================                                     |  55%   69 MB
|=============================================                                     |  55%   69 MB
|==============================================                                    |  55%   69 MB
|==============================================                                    |  55%   69 MB
|==============================================                                    |  55%   69 MB
|==============================================                                    |  55%   70 MB
|==============================================                                    |  55%   70 MB
|==============================================                                    |  55%   70 MB
|==============================================                                    |  56%   70 MB
|==============================================                                    |  56%   70 MB
|==============================================                                    |  56%   70 MB
|==============================================                                    |  56%   70 MB
|==============================================                                    |  56%   70 MB
|==============================================                                    |  56%   70 MB
|==============================================                                    |  56%   71 MB
|===============================================                                   |  56%   71 MB
|===============================================                                   |  56%   71 MB
|===============================================                                   |  56%   71 MB
|===============================================                                   |  56%   71 MB
|===============================================                                   |  57%   71 MB
|===============================================                                   |  57%   71 MB
|===============================================                                   |  57%   71 MB
|===============================================                                   |  57%   72 MB
|===============================================                                   |  57%   72 MB
|===============================================                                   |  57%   72 MB
|===============================================                                   |  57%   72 MB
|===============================================                                   |  57%   72 MB
|===============================================                                   |  57%   72 MB
|================================================                                  |  57%   72 MB
|================================================                                  |  57%   72 MB
|================================================                                  |  58%   72 MB
|================================================                                  |  58%   73 MB
|================================================                                  |  58%   73 MB
|================================================                                  |  58%   73 MB
|================================================                                  |  58%   73 MB
|================================================                                  |  58%   73 MB
|================================================                                  |  58%   73 MB
|================================================                                  |  58%   73 MB
|================================================                                  |  58%   73 MB
|================================================                                  |  58%   73 MB
|================================================                                  |  58%   74 MB
|=================================================                                 |  59%   74 MB
|=================================================                                 |  59%   74 MB
|=================================================                                 |  59%   74 MB
|=================================================                                 |  59%   74 MB
|=================================================                                 |  59%   74 MB
|=================================================                                 |  59%   74 MB
|=================================================                                 |  59%   74 MB
|=================================================                                 |  59%   74 MB
|=================================================                                 |  59%   75 MB
|=================================================                                 |  59%   75 MB
|=================================================                                 |  59%   75 MB
|=================================================                                 |  60%   75 MB
|=================================================                                 |  60%   75 MB
|==================================================                                |  60%   75 MB
|==================================================                                |  60%   75 MB
|==================================================                                |  60%   75 MB
|==================================================                                |  60%   76 MB
|==================================================                                |  60%   76 MB
|==================================================                                |  60%   76 MB
|==================================================                                |  60%   76 MB
|==================================================                                |  60%   76 MB
|==================================================                                |  61%   76 MB
|==================================================                                |  61%   76 MB
|==================================================                                |  61%   76 MB
|==================================================                                |  61%   76 MB
|==================================================                                |  61%   77 MB
|===================================================                               |  61%   77 MB
|===================================================                               |  61%   77 MB
|===================================================                               |  61%   77 MB
|===================================================                               |  61%   77 MB
|===================================================                               |  61%   77 MB
|===================================================                               |  61%   77 MB
|===================================================                               |  62%   77 MB
|===================================================                               |  62%   77 MB
|===================================================                               |  62%   78 MB
|===================================================                               |  62%   78 MB
|===================================================                               |  62%   78 MB
|===================================================                               |  62%   78 MB
|===================================================                               |  62%   78 MB
|===================================================                               |  62%   78 MB
|====================================================                              |  62%   78 MB
|====================================================                              |  62%   78 MB
|====================================================                              |  62%   79 MB
|====================================================                              |  63%   79 MB
|====================================================                              |  63%   79 MB
|====================================================                              |  63%   79 MB
|====================================================                              |  63%   79 MB
|====================================================                              |  63%   79 MB
|====================================================                              |  63%   79 MB
|====================================================                              |  63%   79 MB
|====================================================                              |  63%   79 MB
|====================================================                              |  63%   80 MB
|====================================================                              |  63%   80 MB
|=====================================================                             |  63%   80 MB
|=====================================================                             |  64%   80 MB
|=====================================================                             |  64%   80 MB
|=====================================================                             |  64%   80 MB
|=====================================================                             |  64%   80 MB
|=====================================================                             |  64%   80 MB
|=====================================================                             |  64%   80 MB
|=====================================================                             |  64%   81 MB
|=====================================================                             |  64%   81 MB
|=====================================================                             |  64%   81 MB
|=====================================================                             |  64%   81 MB
|=====================================================                             |  64%   81 MB
|=====================================================                             |  65%   81 MB
|======================================================                            |  65%   81 MB
|======================================================                            |  65%   81 MB
|======================================================                            |  65%   82 MB
|======================================================                            |  65%   82 MB
|======================================================                            |  65%   82 MB
|======================================================                            |  65%   82 MB
|======================================================                            |  65%   82 MB
|======================================================                            |  65%   82 MB
|======================================================                            |  65%   82 MB
|======================================================                            |  65%   82 MB
|======================================================                            |  66%   82 MB
|======================================================                            |  66%   83 MB
|======================================================                            |  66%   83 MB
|=======================================================                           |  66%   83 MB
|=======================================================                           |  66%   83 MB
|=======================================================                           |  66%   83 MB
|=======================================================                           |  66%   83 MB
|=======================================================                           |  66%   83 MB
|=======================================================                           |  66%   83 MB
|=======================================================                           |  66%   83 MB
|=======================================================                           |  66%   84 MB
|=======================================================                           |  67%   84 MB
|=======================================================                           |  67%   84 MB
|=======================================================                           |  67%   84 MB
|=======================================================                           |  67%   84 MB
|=======================================================                           |  67%   84 MB
|========================================================                          |  67%   84 MB
|========================================================                          |  67%   84 MB
|========================================================                          |  67%   85 MB
|========================================================                          |  67%   85 MB
|========================================================                          |  67%   85 MB
|========================================================                          |  67%   85 MB
|========================================================                          |  68%   85 MB
|========================================================                          |  68%   85 MB
|========================================================                          |  68%   85 MB
|========================================================                          |  68%   85 MB
|========================================================                          |  68%   85 MB
|========================================================                          |  68%   86 MB
|========================================================                          |  68%   86 MB
|=========================================================                         |  68%   86 MB
|=========================================================                         |  68%   86 MB
|=========================================================                         |  68%   86 MB
|=========================================================                         |  68%   86 MB
|=========================================================                         |  69%   86 MB
|=========================================================                         |  69%   86 MB
|=========================================================                         |  69%   86 MB
|=========================================================                         |  69%   87 MB
|=========================================================                         |  69%   87 MB
|=========================================================                         |  69%   87 MB
|=========================================================                         |  69%   87 MB
|=========================================================                         |  69%   87 MB
|=========================================================                         |  69%   87 MB
|==========================================================                        |  69%   87 MB
|==========================================================                        |  70%   87 MB
|==========================================================                        |  70%   88 MB
|==========================================================                        |  70%   88 MB
|==========================================================                        |  70%   88 MB
|==========================================================                        |  70%   88 MB
|==========================================================                        |  70%   88 MB
|==========================================================                        |  70%   88 MB
|==========================================================                        |  70%   88 MB
|==========================================================                        |  70%   88 MB
|==========================================================                        |  70%   88 MB
|==========================================================                        |  70%   89 MB
|==========================================================                        |  70%   89 MB
|===========================================================                       |  71%   89 MB
|===========================================================                       |  71%   89 MB
|===========================================================                       |  71%   89 MB
|===========================================================                       |  71%   89 MB
|===========================================================                       |  71%   89 MB
|===========================================================                       |  71%   89 MB
|===========================================================                       |  71%   89 MB
|===========================================================                       |  71%   90 MB
|===========================================================                       |  71%   90 MB
|===========================================================                       |  71%   90 MB
|===========================================================                       |  71%   90 MB
|===========================================================                       |  72%   90 MB
|===========================================================                       |  72%   90 MB
|===========================================================                       |  72%   90 MB
|============================================================                      |  72%   90 MB
|============================================================                      |  72%   90 MB
|============================================================                      |  72%   91 MB
|============================================================                      |  72%   91 MB
|============================================================                      |  72%   91 MB
|============================================================                      |  72%   91 MB
|============================================================                      |  72%   91 MB
|============================================================                      |  73%   91 MB
|============================================================                      |  73%   91 MB
|============================================================                      |  73%   91 MB
|============================================================                      |  73%   92 MB
|============================================================                      |  73%   92 MB
|============================================================                      |  73%   92 MB
|=============================================================                     |  73%   92 MB
|=============================================================                     |  73%   92 MB
|=============================================================                     |  73%   92 MB
|=============================================================                     |  73%   92 MB
|=============================================================                     |  73%   92 MB
|=============================================================                     |  74%   92 MB
|=============================================================                     |  74%   93 MB
|=============================================================                     |  74%   93 MB
|=============================================================                     |  74%   93 MB
|=============================================================                     |  74%   93 MB
|=============================================================                     |  74%   93 MB
|=============================================================                     |  74%   93 MB
|=============================================================                     |  74%   93 MB
|==============================================================                    |  74%   93 MB
|==============================================================                    |  74%   93 MB
|==============================================================                    |  74%   94 MB
|==============================================================                    |  75%   94 MB
|==============================================================                    |  75%   94 MB
|==============================================================                    |  75%   94 MB
|==============================================================                    |  75%   94 MB
|==============================================================                    |  75%   94 MB
|==============================================================                    |  75%   94 MB
|==============================================================                    |  75%   94 MB
|==============================================================                    |  75%   94 MB
|==============================================================                    |  75%   95 MB
|==============================================================                    |  75%   95 MB
|==============================================================                    |  75%   95 MB
|===============================================================                   |  75%   95 MB
|===============================================================                   |  76%   95 MB
|===============================================================                   |  76%   95 MB
|===============================================================                   |  76%   95 MB
|===============================================================                   |  76%   95 MB
|===============================================================                   |  76%   96 MB
|===============================================================                   |  76%   96 MB
|===============================================================                   |  76%   96 MB
|===============================================================                   |  76%   96 MB
|===============================================================                   |  76%   96 MB
|===============================================================                   |  76%   96 MB
|===============================================================                   |  77%   96 MB
|===============================================================                   |  77%   96 MB
|================================================================                  |  77%   96 MB
|================================================================                  |  77%   97 MB
|================================================================                  |  77%   97 MB
|================================================================                  |  77%   97 MB
|================================================================                  |  77%   97 MB
|================================================================                  |  77%   97 MB
|================================================================                  |  77%   97 MB
|================================================================                  |  77%   97 MB
|================================================================                  |  77%   97 MB
|================================================================                  |  78%   97 MB
|================================================================                  |  78%   98 MB
|================================================================                  |  78%   98 MB
|=================================================================                 |  78%   98 MB
|=================================================================                 |  78%   98 MB
|=================================================================                 |  78%   98 MB
|=================================================================                 |  78%   98 MB
|=================================================================                 |  78%   98 MB
|=================================================================                 |  78%   98 MB
|=================================================================                 |  78%   99 MB
|=================================================================                 |  78%   99 MB
|=================================================================                 |  79%   99 MB
|=================================================================                 |  79%   99 MB
|=================================================================                 |  79%   99 MB
|=================================================================                 |  79%   99 MB
|=================================================================                 |  79%   99 MB
|=================================================================                 |  79%   99 MB
|==================================================================                |  79%   99 MB
|==================================================================                |  79%  100 MB
|==================================================================                |  79%  100 MB
|==================================================================                |  79%  100 MB
|==================================================================                |  79%  100 MB
|==================================================================                |  80%  100 MB
|==================================================================                |  80%  100 MB
|==================================================================                |  80%  100 MB
|==================================================================                |  80%  100 MB
|==================================================================                |  80%  100 MB
|==================================================================                |  80%  101 MB
|==================================================================                |  80%  101 MB
|==================================================================                |  80%  101 MB
|===================================================================               |  80%  101 MB
|===================================================================               |  80%  101 MB
|===================================================================               |  80%  101 MB
|===================================================================               |  81%  101 MB
|===================================================================               |  81%  101 MB
|===================================================================               |  81%  102 MB
|===================================================================               |  81%  102 MB
|===================================================================               |  81%  102 MB
|===================================================================               |  81%  102 MB
|===================================================================               |  81%  102 MB
|===================================================================               |  81%  102 MB
|===================================================================               |  81%  102 MB
|===================================================================               |  81%  102 MB
|====================================================================              |  81%  102 MB
|====================================================================              |  82%  103 MB
|====================================================================              |  82%  103 MB
|====================================================================              |  82%  103 MB
|====================================================================              |  82%  103 MB
|====================================================================              |  82%  103 MB
|====================================================================              |  82%  103 MB
|====================================================================              |  82%  103 MB
|====================================================================              |  82%  103 MB
|====================================================================              |  82%  103 MB
|====================================================================              |  82%  104 MB
|====================================================================              |  83%  104 MB
|====================================================================              |  83%  104 MB
|=====================================================================             |  83%  104 MB
|=====================================================================             |  83%  104 MB
|=====================================================================             |  83%  104 MB
|=====================================================================             |  83%  104 MB
|=====================================================================             |  83%  104 MB
|=====================================================================             |  83%  105 MB
|=====================================================================             |  83%  105 MB
|=====================================================================             |  83%  105 MB
|=====================================================================             |  83%  105 MB
|=====================================================================             |  84%  105 MB
|=====================================================================             |  84%  105 MB
|=====================================================================             |  84%  105 MB
|=====================================================================             |  84%  105 MB
|======================================================================            |  84%  105 MB
|======================================================================            |  84%  106 MB
|======================================================================            |  84%  106 MB
|======================================================================            |  84%  106 MB
|======================================================================            |  84%  106 MB
|======================================================================            |  84%  106 MB
|======================================================================            |  84%  106 MB
|======================================================================            |  85%  106 MB
|======================================================================            |  85%  106 MB
|======================================================================            |  85%  107 MB
|======================================================================            |  85%  107 MB
|======================================================================            |  85%  107 MB
|======================================================================            |  85%  107 MB
|=======================================================================           |  85%  107 MB
|=======================================================================           |  85%  107 MB
|=======================================================================           |  85%  107 MB
|=======================================================================           |  85%  107 MB
|=======================================================================           |  85%  107 MB
|=======================================================================           |  86%  108 MB
|=======================================================================           |  86%  108 MB
|=======================================================================           |  86%  108 MB
|=======================================================================           |  86%  108 MB
|=======================================================================           |  86%  108 MB
|=======================================================================           |  86%  108 MB
|=======================================================================           |  86%  108 MB
|========================================================================          |  86%  108 MB
|========================================================================          |  86%  109 MB
|========================================================================          |  86%  109 MB
|========================================================================          |  87%  109 MB
|========================================================================          |  87%  109 MB
|========================================================================          |  87%  109 MB
|========================================================================          |  87%  109 MB
|========================================================================          |  87%  109 MB
|========================================================================          |  87%  109 MB
|========================================================================          |  87%  109 MB
|========================================================================          |  87%  110 MB
|========================================================================          |  87%  110 MB
|========================================================================          |  87%  110 MB
|========================================================================          |  87%  110 MB
|=========================================================================         |  87%  110 MB
|=========================================================================         |  88%  110 MB
|=========================================================================         |  88%  110 MB
|=========================================================================         |  88%  110 MB
|=========================================================================         |  88%  110 MB
|=========================================================================         |  88%  111 MB
|=========================================================================         |  88%  111 MB
|=========================================================================         |  88%  111 MB
|=========================================================================         |  88%  111 MB
|=========================================================================         |  88%  111 MB
|=========================================================================         |  88%  111 MB
|=========================================================================         |  89%  111 MB
|=========================================================================         |  89%  111 MB
|==========================================================================        |  89%  111 MB
|==========================================================================        |  89%  112 MB
|==========================================================================        |  89%  112 MB
|==========================================================================        |  89%  112 MB
|==========================================================================        |  89%  112 MB
|==========================================================================        |  89%  112 MB
|==========================================================================        |  89%  112 MB
|==========================================================================        |  89%  112 MB
|==========================================================================        |  89%  112 MB
|==========================================================================        |  89%  112 MB
|==========================================================================        |  90%  113 MB
|==========================================================================        |  90%  113 MB
|==========================================================================        |  90%  113 MB
|==========================================================================        |  90%  113 MB
|===========================================================================       |  90%  113 MB
|===========================================================================       |  90%  113 MB
|===========================================================================       |  90%  113 MB
|===========================================================================       |  90%  113 MB
|===========================================================================       |  90%  113 MB
|===========================================================================       |  90%  114 MB
|===========================================================================       |  90%  114 MB
|===========================================================================       |  91%  114 MB
|===========================================================================       |  91%  114 MB
|===========================================================================       |  91%  114 MB
|===========================================================================       |  91%  114 MB
|===========================================================================       |  91%  114 MB
|===========================================================================       |  91%  114 MB
|============================================================================      |  91%  115 MB
|============================================================================      |  91%  115 MB
|============================================================================      |  91%  115 MB
|============================================================================      |  91%  115 MB
|============================================================================      |  92%  115 MB
|============================================================================      |  92%  115 MB
|============================================================================      |  92%  115 MB
|============================================================================      |  92%  115 MB
|============================================================================      |  92%  116 MB
|============================================================================      |  92%  116 MB
|============================================================================      |  92%  116 MB
|============================================================================      |  92%  116 MB
|=============================================================================     |  92%  116 MB
|=============================================================================     |  92%  116 MB
|=============================================================================     |  93%  116 MB
|=============================================================================     |  93%  116 MB
|=============================================================================     |  93%  117 MB
|=============================================================================     |  93%  117 MB
|=============================================================================     |  93%  117 MB
|=============================================================================     |  93%  117 MB
|=============================================================================     |  93%  117 MB
|=============================================================================     |  93%  117 MB
|=============================================================================     |  93%  117 MB
|=============================================================================     |  93%  117 MB
|=============================================================================     |  93%  117 MB
|==============================================================================    |  94%  118 MB
|==============================================================================    |  94%  118 MB
|==============================================================================    |  94%  118 MB
|==============================================================================    |  94%  118 MB
|==============================================================================    |  94%  118 MB
|==============================================================================    |  94%  118 MB
|==============================================================================    |  94%  118 MB
|==============================================================================    |  94%  118 MB
|==============================================================================    |  94%  118 MB
|==============================================================================    |  94%  119 MB
|==============================================================================    |  94%  119 MB
|==============================================================================    |  95%  119 MB
|==============================================================================    |  95%  119 MB
|===============================================================================   |  95%  119 MB
|===============================================================================   |  95%  119 MB
|===============================================================================   |  95%  119 MB
|===============================================================================   |  95%  119 MB
|===============================================================================   |  95%  119 MB
|===============================================================================   |  95%  120 MB
|===============================================================================   |  95%  120 MB
|===============================================================================   |  95%  120 MB
|===============================================================================   |  95%  120 MB
|===============================================================================   |  96%  120 MB
|===============================================================================   |  96%  120 MB
|===============================================================================   |  96%  120 MB
|===============================================================================   |  96%  120 MB
|===============================================================================   |  96%  121 MB
|================================================================================  |  96%  121 MB
|================================================================================  |  96%  121 MB
|================================================================================  |  96%  121 MB
|================================================================================  |  96%  121 MB
|================================================================================  |  96%  121 MB
|================================================================================  |  96%  121 MB
|================================================================================  |  96%  121 MB
|================================================================================  |  97%  121 MB
|================================================================================  |  97%  122 MB
|================================================================================  |  97%  122 MB
|================================================================================  |  97%  122 MB
|================================================================================  |  97%  122 MB
|================================================================================  |  97%  122 MB
|================================================================================= |  97%  122 MB
|================================================================================= |  97%  122 MB
|================================================================================= |  97%  122 MB
|================================================================================= |  97%  122 MB
|================================================================================= |  97%  123 MB
|================================================================================= |  98%  123 MB
|================================================================================= |  98%  123 MB
|================================================================================= |  98%  123 MB
|================================================================================= |  98%  123 MB
|================================================================================= |  98%  123 MB
|================================================================================= |  98%  123 MB
|================================================================================= |  98%  123 MB
|================================================================================= |  98%  123 MB
|==================================================================================|  98%  124 MB
|==================================================================================|  98%  124 MB
|==================================================================================|  99%  124 MB
|==================================================================================|  99%  124 MB
|==================================================================================|  99%  124 MB
|==================================================================================|  99%  124 MB
|==================================================================================|  99%  124 MB
|==================================================================================|  99%  124 MB
|==================================================================================|  99%  125 MB
|==================================================================================|  99%  125 MB
|==================================================================================|  99%  125 MB
|==================================================================================|  99%  125 MB
|==================================================================================|  99%  125 MB
|===================================================================================| 100%  125 MB

## Convert characters to factors
# Note, if we weren't concatenating,
# this could be done while reading 
# by specifying 
# `COL_NAME = col_factor(levels=NULL)`
# inside cols_only()
df = mutate_if(
  df,
  is.character,
  as.factor
)
print(dim(df))

[1] 370461     10

head(df)

Rename and reorder columns

## Rename
col_name_map = list(
  CHR = 'Chromosome',
  START = 'Start_Position',
  END = 'End_Position',
  GENE = 'SYMBOL',
  REF = 'Reference_Allele',
  ALT = 'Allele',
  CLASS = 'Variant_Classification',
  IMPACT = 'IMPACT',
  TYPE = 'Variant_Type',
  BARCODE = 'Tumor_Sample_Barcode'
)
df = rename(df, !!! col_name_map)
## Reorder
keep_cols = names(col_name_map)
df = select(df, keep_cols)
head(df)

Fill missing data

levels(df$GENE) = c(levels(df$GENE), 'INTERGENIC')
df$GENE[is.na(df$GENE)] = 'INTERGENIC'

Create new columns from string ops

df$SAMPLE = str_sub(df$BARCODE, 1, 12)
df$MUTATION = paste(
  df$CHR, 
  df$GENE,
  df$START,
  df$END,
  df$REF,
  df$ALT,
  sep = ':'
)
## Convert new columns to factors
## if applicable
df$SAMPLE = as.factor(df$SAMPLE)
df$MUTATION = as.factor(df$MUTATION)

Remove duplicates

## Remove duplicate rows
df = unique(df)
## Remove duplicate based on column
df_mut = df[!duplicated(df$MUTATION),]
print(dim(df))

[1] 132916     12

print(dim(df_mut))

[1] 130625     12

Remove columns

drop_cols = c('BARCODE', 'SAMPLE')
df_mut = select(df_mut, -one_of(drop_cols))
print(dim(df_mut))

[1] 130625     10

head(df_mut)

New columns from delimited column

## Create dummy frame
df_tmp = df
drop_cols = c(
    'CHR',
    'GENE',
    'START',
    'END',
    'REF',
    'ALT'
)
df_tmp = select(df_tmp, -one_of(drop_cols))
## Create new columns
df_tmp = separate(
  df_tmp,
  MUTATION,
  drop_cols,
  ':'
)
print(dim(df_tmp))

[1] 132916     11

head(df_tmp)

Writing files

write_delim(
  df, 
  'data/out/df_r.tsv', 
  delim = '\t'
)

Read & write binary files

rds_path = 'data/out/df.rds'

## Write
saveRDS(df, rds_path)

## Read
df = readRDS(rds_path)

Long to wide

## Shorten to relevant columns
# Note, we could include other columns here
# like GENE and IMPACT, but we won't 
# to match the python example.

## Create a dummy column w/ fill value
df_tmp = select(df, c('SAMPLE', 'MUTATION'))
df_tmp$EXISTS = 1

## Long-to-wide
df_wide = spread(
  df_tmp,
  key = 'SAMPLE',
  value = 'EXISTS',
  fill = 0
)
rm(df_tmp)

print(dim(df_wide))
head(df_wide)

Merge

## Select columns to add on and col to join on
cols = c('MUTATION', 'GENE', 'IMPACT')

## Merge
df_wide = merge(
  df_wide, select(df_mut, cols),
  by = 'MUTATION',
  all.x = TRUE
)

## Re-order columns
# Put new columns first
df_wide = select(df_wide, cols, everything())

# Note, first 3 columns are out of order 
# w/ python example.
print(dim(df_wide))
head(df_wide)

Wide to long

# Set value and id columns
value_cols = grep('TCGA-', names(df_wide), value = TRUE)

# Melt
df_long = gather(
  df_wide,
  key = 'SAMPLE',
  value = 'EXISTS',
  value_cols
)

# Clean up
df_long = filter(df_long, EXISTS != 0)
df_long = select(df_long, -EXISTS)

print(dim(df_long))
head(df_long)

Free memory

rm(df_wide, df_long)

Counting

Count unique elements

n_genes = length(unique(df$GENE))
n_samples = length(unique(df$SAMPLE))
n_mutations = length(unique(df$MUTATION))
n_mutation_classes = length(unique(df$CLASS))


print('Number of unique')
cat('\tSamples: ', n_samples, '\n')
cat('\tGenes: ', n_genes, '\n')
cat('\tMutations: ', n_mutations, '\n')
cat('\tMutation Classes: ', n_mutation_classes, '\n')

Count by factor levels

class_counts = sort(summary(df$CLASS), decreasing = TRUE)
impact_counts = sort(summary(df$IMPACT), decreasing = TRUE)
type_counts = sort(summary(df$TYPE), decreasing = TRUE)

print('Counts per CLASS:')
print(class_counts)
print('Counts per IMPACT:')
print(impact_counts)
print('Counts per TYPE:')
print(type_counts)

## Display some instances
# Need to override the maxsum = 50 arg
mut_counts =  sort(
  summary(df$MUTATION, maxsum = n_mutations), 
  decreasing = TRUE)
print('Top repeated (>10) mutations:')
print(mut_counts[mut_counts > 10])

sample_counts =  sort(
  summary(df$SAMPLE, maxsum = n_samples), 
  decreasing = TRUE)
print('Samples with most mutations:')
print(sample_counts[0:10])
print('Samples with least mutations:')
print(tail(sample_counts, 10))

Summarize by group

df_summary = df %>%
  group_by(GENE) %>%
  summarise(
    N_MUTATIONS = n(),
    N_UNIQUE_MUTATIONS = n_distinct(MUTATION),
    N_SAMPLES = n_distinct(BARCODE)
)
head(df_summary)

Sorting

df_summary = df_summary %>%
  arrange(desc(N_SAMPLES), N_MUTATIONS)
head(df_summary)

Summarize by multiple groups

df_impact = df %>%
  group_by(GENE, IMPACT) %>%
  summarise(COUNT = n_distinct(MUTATION))

print(dim(df_impact))
head(df_impact)

Visualizations

Use cowplot for nice theme and subplotting https://cran.r-project.org/web/packages/cowplot/vignettes/introduction.html

img_dir = 'data/out/img/'

Ranking

NOTE: shape = ‘4’ corresponds to X’s

x = 0:(n_samples-1)
y = unname(sample_counts)

p = ggplot(mapping = aes(x, y)) +
  geom_line() +
  geom_point(shape = 4) +
  ggtitle('Mutations per Individual') +
  xlab('Individual Rank') +
  ylab('Number of Mutations')
 

p
ggsave(paste0(img_dir, 'rank_r.png')) 

Bar plot

p = ggplot(
    mapping = aes(names(class_counts), unname(class_counts))
  ) +
  geom_bar(stat = 'identity') +
  scale_x_discrete(limits = rev(names(class_counts))) +
  coord_flip()

p
ggsave(paste0(img_dir, 'bar_r.png'))

Subplots

## First plot
# Reuse instance from above
p1 = p

## Second plot
n_genes_to_plot = 5
genes = df_summary$GENE[0:n_genes_to_plot]
counts = df_summary$N_SAMPLES[0:n_genes_to_plot]
p2 = ggplot(mapping = aes(genes, counts)) +
  geom_bar(stat = 'identity') +
  scale_x_discrete(limits = genes)
  
p_grid = plot_grid(p1, p2, ncol = 2)
save_plot(paste0(img_dir, 'subplot_r.png'), p_grid, ncol = 2)

Count vs identity

## New df's for plotting
df_identity = df_summary %>%
  arrange(-N_MUTATIONS)
df_count = df

## Plot params
n_genes_to_plot = 5
genes = df_identity$GENE[0:n_genes_to_plot]
counts = df_identity$N_MUTATIONS[0:n_genes_to_plot]

## Identity plot
p1 = ggplot(mapping = aes(genes, counts)) +
  geom_bar(stat = 'identity') + 
  scale_x_discrete(limits = genes) +
  ggtitle('# Mutations - Identity')

## Count plot
p2 = ggplot(df, aes(GENE)) +
  geom_bar() +
  scale_x_discrete(limits = genes) + 
  ggtitle('# Mutations - Count')

p_grid = plot_grid(p1, p2, ncol = 2)
save_plot(paste0(img_dir, 'count_vs_identity_r.png'), p_grid, ncol = 2)
p_grid

Plot with grouping

## Plot params
n_genes_to_plot = 5
genes = df_summary$GENE[0:n_genes_to_plot]

## Filter to relvant data
df_plt = df_impact %>%
  filter(GENE %in% genes)

## Reorder for plot
# This is an alternative to 
# scale_x_discrete(limits=genes)
df_plt$GENE = factor(df_plt$GENE, levels = genes)

p = ggplot(data = df_plt) +
  geom_bar(
    aes(x=GENE, y=COUNT, fill=IMPACT),
    stat = 'identity',
    position = 'dodge'
  ) +
  scale_fill_brewer(
    type='qual',
    palette = 'Set1'
  ) +
  ggtitle('Impact of Mutations')
p
ggsave(paste0(img_dir, 'group_r.png'), p)

Faceted plot

## Get some samples and genes
samples = names(sample_counts[0:2])
genes = c('PIK3CA', 'TTN', 'MUC16')

## Filter to relevant data
df_plt = df %>%
  filter(SAMPLE %in% samples & GENE %in% genes)

## Reorder
df_plt$GENE = factor(df_plt$GENE, levels = genes)
df_plt$SAMPLE = factor(df_plt$SAMPLE, levels = samples)

## Plot
p = ggplot(df_plt) +
  geom_bar(
    aes(x=GENE, fill=IMPACT),
    position = 'dodge'
  ) + 
  scale_fill_brewer(
    type='qual',
    palette = 'Set1'
  ) +
  facet_wrap('SAMPLE')

p
ggsave(paste0(img_dir, 'facet_r.png'), p)